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花方 信孝
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305-0047 茨城県つくば市千現1-2-1 [アクセス]
  • 論文・発表

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研究論文 TSV

2018
  1. Peng Pei, Fan Yang, Jiaxing Liu, Haoran Hu, Xiaoyu Du, Nobutaka Hanagata, Shichang Zhao, Yufang Zhu. Composite-dissolving microneedle patches for chemotherapy and photothermal therapy in superficial tumor treatment. Biomaterials Science. 6 [6] (2018) 1414-1423 10.1039/c8bm00005k
  2. Zhengfang Tian, Xia Yu, Zhijun Ruan, Min Zhu, Yufang Zhu, Nobutaka Hanagata. Magnetic mesoporous silica nanoparticles coated with thermo-responsive copolymer for potential chemo- and magnetic hyperthermia therapy. Microporous and Mesoporous Materials. 256 (2018) 1-9 10.1016/j.micromeso.2017.07.053
2017
  1. Arun Kumar Manoharan, Shanmugavel Chinnathambi, Ramasamy Jayavel, Nobutaka Hanagata. Simplified detection of the hybridized DNA using a graphene field effect transistor. Science and Technology of Advanced Materials. 18 [1] (2017) 43-50 10.1080/14686996.2016.1253408
  2. Min-Hua Chen, Yi-Jhen Jenh, Sheng-Kai Wu, Yo-Shen Chen, Nobutaka Hanagata, Feng-Huei Lin. Non-invasive Photodynamic Therapy in Brain Cancer by Use of Tb3+-Doped LaF3 Nanoparticles in Combination with Photosensitizer Through X-ray Irradiation: A Proof-of-Concept Study. Nanoscale Research Letters. 12 [1] (2017) 10.1186/s11671-017-1840-3
  3. Nobutaka Hanagata, Xianglan Li, Min-Hua Chen, Jie Li, Shinya Hattori. Double-stranded phosphodiester cytosine-guanine oligodeoxynucleotide complexed with calcium phosphate as a potent vaccine adjuvant for activating cellular and Th1-type humoral immunities. International Journal of Nanomedicine. Volume 13 (2017) 43-62 10.2217/nnm-2017-0237
  4. 花方 信孝. 特集に寄せて-バイオマテリアルデザインのためのインフォマティクス-. バイオマテリアル. 35 [3] (2017) 154-155
  5. Tao Liang, Shuang Xie, Weifei Fu, Yu Cai, Chinnathambi Shanmugavel, Hideo Iwai, Daisuke Fujita, Nobutaka Hanagata, Hongzheng Chen, Mingsheng Xu. Synthesis and fast transfer of monolayer MoS2 on reusable fused silica. Nanoscale. 9 [21] (2017) 6984-6990 10.1039/c7nr01755c
  6. Shuang Xie, Mingsheng Xu, Shuyun Huang, Tao Liang, Shengping Wang, Hongfei Li, Hideo Iwai, Keiko Onishi, Nobutaka Hanagata, Daisuke Fujita, Xiangyang Ma, Deren Yang. Inhomogeneous composition distribution in monolayer transition metal dichalcogenide alloys. Materials Research Express. 4 [4] (2017) 045004 10.1088/2053-1591/aa6859
  7. Tao Liang, Shuang Xie, Zhuoting Huang, Weifei Fu, Yu Cai, Xi Yang, Hongzheng Chen, Xiangyang Ma, Hideo Iwai, Daisuke Fujita, Nobutaka Hanagata, Mingsheng Xu. Elucidation of Zero-Dimensional to Two-Dimensional Growth Transition in MoS2Chemical Vapor Deposition Synthesis. Advanced Materials Interfaces. 4 [4] (2017) 1600687 10.1002/admi.201600687
  8. Xianxian Yao, Zhengfang Tian, Jiaxing Liu, Yufang Zhu, Nobutaka Hanagata. Mesoporous Silica Nanoparticles Capped with Graphene Quantum Dots for Potential Chemo–Photothermal Synergistic Cancer Therapy. Langmuir. 33 [2] (2017) 591-599 10.1021/acs.langmuir.6b04189
  9. Shanmugavel Chinnathambi, Norhidayah Abu, Nobutaka Hanagata. Biocompatible CdSe/ZnS quantum dot micelles for long-term cell imaging without alteration to the native structure of the blood plasma protein human serum albumin. RSC Advances. 7 [5] (2017) 2392-2402 10.1039/c6ra26592h
  10. Xia Li, Xiupeng Wang, Jun Zhang, Nobutaka Hanagata, Xuebin Wang, Qunhong Weng, Atsuo Ito, Yoshio Bando, Dmitri Golberg. Hollow boron nitride nanospheres as boron reservoir for prostate cancer treatment. Nature Communications. 8 (2017) 13936 10.1038/ncomms13936
  11. Nobutaka Hanagata. CpG oligodeoxynucleotide nanomedicines for the prophylaxis or treatment of cancers, infectious diseases, and allergies. International Journal of Nanomedicine. Volume 12 (2017) 515-531 10.2147/ijn.s114477
2016
  1. 花方 信孝. ワクチンアジュバントとしてのDNAナノメディシンの開発. 化学工業. 67 [11] (2016) 807-813
  2. Eri Hirata, Eijiro Miyako, Nobutaka Hanagata, Natsumi Ushijima, Norihito Sakaguchi, Julie Russier, Masako Yudasaka, Sumio Iijima, Alberto Bianco, Atsuro Yokoyama. Carbon nanohorns allow acceleration of osteoblast differentiation via macrophage activation. Nanoscale. 8 [30] (2016) 14514-14522 10.1039/c6nr02756c
  3. Min-Hua Chen, Nobutaka Hanagata, Toshiyuki Ikoma, Jian-Yuan Huang, Keng-Yuan Li, Chun-Pin Lin, Feng-Huei Lin. Hafnium-doped hydroxyapatite nanoparticles with ionizing radiation for lung cancer treatment. Acta Biomaterialia. 37 (2016) 165-173 10.1016/j.actbio.2016.04.004
  4. Shanmugavel Chinnathambi. Underlying the Mechanism of 5-Fluorouracil and Human Serum Albumin Interaction: A Biophysical Study. Journal of Physical Chemistry & Biophysics. 6 [2] (2016) 10.4172/2161-0398.1000214
  5. Song Chen, Xinxin Du, Lan Jia, Haixin Chang, Toshiyuki Ikoma, Nobutaka Hanagata. Synthesis and osteo-compatibility of novel reduced graphene oxide–aminosilica hybrid nanosheets. Materials Science and Engineering: C. 61 (2016) 251-256 10.1016/j.msec.2015.12.056
  6. Yi Xu, Yufang Zhu, Xianglan Li, Hiromi Morita, Nobutaka Hanagata. Investigation of dendritic mesoporous silica nanoparticles for cytosine-phosphate-guanosine oligodeoxynucleotide delivery. Materials Express. 6 [2] (2016) 116-126 10.1166/mex.2016.1288
  7. Nobutaka Hanagata. IFITM5 mutations and osteogenesis imperfecta. Journal of Bone and Mineral Metabolism. 34 [2] (2016) 123-131 10.1007/s00774-015-0667-1
2015
  1. K. Shiba, M. Tagaya, T. Sugiyama, N. Hanagata. Preparation of luminescent titania/dye hybrid nanoparticles and their dissolution properties for controlling cellular environments. RSC Advances. 5 [126] (2015) 104343-104353 10.1039/c5ra23026h
  2. Shanmugavel Chinnathambi, Xiaodong Pi, Mingsheng Xu, Nobutaka Hanagata. Regulation of bifurcated cytokine induction by surface charge of nanoparticles during interaction between CpG oligodeoxynucleotides and toll-like receptor 9. Journal of Drug Delivery Science and Technology. 29 (2015) 251-260 10.1016/j.jddst.2015.08.008
  3. Nien-Chi Huang, Qingmin Ji, Tomohiko Yamazaki, Waka Nakanishi, Nobutaka Hanagata, Katsuhiko Ariga, Shan-hui Hsu. Gene transfer on inorganic/organic hybrid silica nanosheets. Physical Chemistry Chemical Physics. 17 [38] (2015) 25455-25462 10.1039/c5cp03483c
  4. Nobutaka Hanagata, Hiromi Morita. Calcium ions rescue human lung epithelial cells from the toxicity of zinc oxide nanoparticles. The Journal of Toxicological Sciences. 40 [5] (2015) 625-635 10.2131/jts.40.625
  5. Shimpei Maeda, Takanori Morikawa, Tatsuyuki Takadate, Takashi Suzuki, Takashi Minowa, Nobutaka Hanagata, Tohru Onogawa, Fuyuhiko Motoi, Toshihide Nishimura, Michiaki Unno. Mass spectrometry-based proteomic analysis of formalin-fixed paraffin-embedded extrahepatic cholangiocarcinoma. Journal of Hepato-Biliary-Pancreatic Sciences. 22 [9] (2015) 683-691 10.1002/jhbp.262
  6. Mo Dan, Liming Xu, Anliang Shao, Xiang Cheng, Cuiping Zhang, Robert Yokel, Taro Takemura, Nobutaka Hanagata, Masami Niwa, Daisuke Watanabe. Silver nanoparticles induce tight junction disruption and astrocyte neurotoxicity in a rat blood–brain barrier primary triple coculture model. International Journal of Nanomedicine. (2015) 6105 10.2147/ijn.s85265
  7. Song Chen, Qiqing Zhang, Lan Jia, Xinxin Du, Nobutaka Hanagata. A facilely controlled length, cytotoxicity, length-dependent and cell type-dependent cellular uptake of silica nanotubes and their applications in the delivery of immunostimulatory CpG oligodeoxynucleotides. Journal of Materials Chemistry B. 3 [36] (2015) 7246-7254 10.1039/c5tb01270h
  8. Huijie Zhang, Shini Feng, Ting Yan, Chunyi Zhi, Xiao-Dong Gao, Nobutaka Hanagata. Polyethyleneimine-functionalized boron nitride nanospheres as efficient carriers for enhancing the immunostimulatory effect of CpG oligodeoxynucleotides. International Journal of Nanomedicine. (2015) 5343 10.2147/ijn.s88774
  9. Venkata Krishnan, Yuki Kasuya, Qingmin Ji, Marappan Sathish, Lok Kumar Shrestha, Shinsuke Ishihara, Kosuke Minami, Hiromi Morita, Tomohiko Yamazaki, Nobutaka Hanagata, Kun’ichi Miyazawa, Somobrata Acharya, Waka Nakanishi, Jonathan P. Hill, Katsuhiko Ariga. Vortex-Aligned Fullerene Nanowhiskers as a Scaffold for Orienting Cell Growth. ACS Applied Materials & Interfaces. 7 [28] (2015) 15667-15673 10.1021/acsami.5b04811
  10. Yi Xu, Peter Claiden, Yufang Zhu, Hiromi Morita, Nobutaka Hanagata. Effect of amino groups of mesoporous silica nanoparticles on CpG oligodexynucleotide delivery. Science and Technology of Advanced Materials. 16 [4] (2015) 045006 10.1088/1468-6996/16/4/045006
  11. HANAGATA, Nobutaka. Global Gene Expression Analysis for the Assessment of Nanobiomaterials. Biomaterials for Oral and Craniomaxillofacial Applications. 17 (2015) 78-89 10.1159/000381695
  12. Shanmugavel Chinnathambi, Subramani Karthikeyan, Devadasan Velmurugan, Nobutaka Hanagata, Prakasarao Aruna, Singaravelu Ganesan. Investigations on the Interactions of 5-Fluorouracil with Herring Sperm DNA: Steady State/Time Resolved and Molecular Modeling Studies. Biophysical Reviews and Letters. 10 [02] (2015) 115-133 10.1142/s1793048015500034
  13. Cuilian Tao, Yufang Zhu, Xianglan Li, Nobutaka Hanagata. Binding of CpG oligodeoxynucleotides to mesoporous silica nanoparticles for enhancing delivery efficiency. Microporous and Mesoporous Materials. 204 (2015) 91-98 10.1016/j.micromeso.2014.11.007
  14. 花方 信孝. NIMS分子・物質合成プラットフォームーイノベーション技術の創出. 工業材料. 63 [3] (2015) 76-78
  15. Shanmugavel Chinnathambi, Subramani Karthikeyan, Devadasan Velmurugan, Nobutaka Hanagata, Prakasarao Aruna, Singaravelu Ganesan. Effect of Moderate UVC Irradiation on Bovine Serum Albumin and Complex with Antimetabolite 5-Fluorouracil: Fluorescence Spectroscopic and Molecular Modelling Studies. International Journal of Spectroscopy. 2015 (2015) 1-12 10.1155/2015/315764
2014
  1. Sachiro Kakinoki, Yusuke Sakai, Taro Takemura, Nobutaka Hanagata, Toshia Fujisato, Kazuhiko Ishihara, Tetsuji Yamaoka. Gene chip/PCR-array analysis of tissue response to 2-methacryloyloxyethyl phosphorylcholine (MPC) polymer surfaces in a mouse subcutaneous transplantation system. Journal of Biomaterials Science, Polymer Edition. 25 [14-15] (2014) 1658-1672 10.1080/09205063.2014.939917
  2. Gabriela Furlan, Takashi Minowa, Nobutaka Hanagata, Chiho Kataoka-Hamai, Yoshihisa Kaizuka. Phosphatase CD45 Both Positively and Negatively Regulates T Cell Receptor Phosphorylation in Reconstituted Membrane Protein Clusters. Journal of Biological Chemistry. 289 [41] (2014) 28514-28525 10.1074/jbc.m114.574319
  3. Min-Hua Chen, Tomohiko Yoshioka, Toshiyuki Ikoma, Nobutaka Hanagata, Feng-Huei Lin, Junzo Tanaka. Photoluminescence and doping mechanism of theranostic Eu3+/Fe3+dual-doped hydroxyapatite nanoparticles. Science and Technology of Advanced Materials. 15 [5] (2014) 055005 10.1088/1468-6996/15/5/055005
  4. Cuilian Tao, Yufang Zhu, Xianglan Li, Nobutaka Hanagata. Magnetic mesoporous silica nanoparticles for CpG delivery to enhance cytokine induction via toll-like receptor 9. RSC Adv.. 4 [86] (2014) 45823-45830 10.1039/c4ra08003c
  5. Shanmugavel Chinnathambi, Devadasan Velmurugan, Nobutaka Hanagata, Prakasa Rao Aruna, Singaravelu Ganesan. Investigations on the interactions of 5-fluorouracil with bovine serum albumin: Optical spectroscopic and molecular modeling studies. Journal of Luminescence. 151 (2014) 1-10 10.1016/j.jlumin.2014.01.063
  6. Qunhong Weng, Binju Wang, Xuebin Wang, Nobutaka Hanagata, Xia Li, Dequan Liu, Xi Wang, Xiangfen Jiang, Yoshio Bando, Dmitri Golberg. Highly Water-Soluble, Porous, and Biocompatible Boron Nitrides for Anticancer Drug Delivery. ACS Nano. 8 [6] (2014) 6123-6130 10.1021/nn5014808
  7. Xi Yang, Jie Li, Tao Liang, Chunyan Ma, Yingying Zhang, Hongzheng Chen, Nobutaka Hanagata, Huanxing Su, Mingsheng Xu. Antibacterial activity of two-dimensional MoS2 sheets. Nanoscale. 6 [17] (2014) 10126-10133 10.1039/c4nr01965b
  8. Song Chen, Xuetao Shi, Akiyoshi Osaka, Hong Gao, Nobutaka Hanagata. Facile synthesis, microstructure and BMP-2 delivery of novel silica hollow flowers for enhanced osteoblast differentiation. Chemical Engineering Journal. 246 (2014) 1-9 10.1016/j.cej.2014.02.053
  9. Kota Shiba, Motohiro Tagaya, Nobutaka Hanagata. Synthesis of Cytocompatible Luminescent Titania/Fluorescein Hybrid Nanoparticles. ACS Applied Materials & Interfaces. 6 [9] (2014) 6825-6834 10.1021/am500636d
  10. 花方 信孝. ナノ粒子を使ってDNA医薬の作用を操る. 現代科学. 4 [517] (2014) 44-50
  11. Xia Li, Nobutaka Hanagata, Xuebin Wang, Maho Yamaguchi, Wei Yi, Yoshio Bando, Dmitri Golberg. Multimodal luminescent-magnetic boron nitride nanotubes@NaGdF4:Eu structures for cancer therapy. Chem. Commun.. 50 [33] (2014) 4371-4374 10.1039/c4cc00990h
  12. Song Chen, Huijie Zhang, Xuetao Shi, Hongkai Wu, Nobutaka Hanagata. Microfluidic generation of chitosan/CpG oligodeoxynucleotide nanoparticles with enhanced cellular uptake and immunostimulatory properties. Lab on a Chip. 14 [11] (2014) 1842 10.1039/c4lc00015c
  13. 花方 信孝. 花粉症治療のためのDNAナノメディシン. ナノ学会会報. 12 [2] (2014) 45-50
  14. 花方 信孝. ナノ粒子によるDNAアジュバントの作用制御ーDDSにおけるナノ粒子の新しい役割ー. MEDICAL SCIENCE DIGEST. 40 [519(2)] (2014) 75-80
  15. 花方 信孝. 網羅的遺伝子発現解析によるナノマテリアルの毒性評価. アレルギーの臨床. 34 [455(3)] (2014) 289-292
  16. Ehashi Tomo, Takemura Taro, Hanagata Nobutaka, Minowa Takashi, Kobayashi Hisatoshi, Ishihara Kazuhiko, Yamaoka Tetsuji, Matsusaki Michiya. Comprehensive Genetic Analysis of Early Host Body Reactions to the Bioactive and Bio-Inert Porous Scaffolds. PLoS ONE. 9 [1] (2014) e85132 10.1371/journal.pone.0085132
  17. Cuilian Tao, Yufang Zhu, Yi Xu, Min Zhu, Hiromi Morita, Nobutaka Hanagata. Mesoporous silica nanoparticles for enhancing the delivery efficiency of immunostimulatory DNA drugs. Dalton Trans.. 43 [13] (2014) 5142-5150 10.1039/c3dt53433b
  18. Shanmugavel Chinnathambi, Song Chen, Singaravelu Ganesan, Nobutaka Hanagata. Silicon Quantum Dots for Biological Applications. Advanced Healthcare Materials. 3 [1] (2014) 10-29 10.1002/adhm.201300157
2013
  1. HANAGATA, Nobutaka. Recognition of Oligodeoxynucleotides by Toll-like Receptor 9: Phosphodiester Backbone vs. Phosphorothioate Backbone and Monomer vs. Multimer. NANO BIOMEDICINE. 5 [2] (2013) 9999-9999
  2. Hideki T. Miyazaki, Takeshi Kasaya, Taro Takemura, Nobutaka Hanagata, Takeshi Yasuda, Hiroshi Miyazaki. Diffraction-unlimited optical imaging of unstained living cells in liquid by electron beam scanning of luminescent environmental cells. Optics Express. 21 [23] (2013) 28198 10.1364/oe.21.028198
  3. 花方 信孝. 免疫活性化DNA医薬のナノ粒子による作用制御. 細胞. 45 [12] (2013) 585-589
  4. Takashi Tsukamoto, Xianglan Li, Hiromi Morita, Takashi Minowa, Tomoyasu Aizawa, Nobutaka Hanagata, Makoto Demura. Role of S-Palmitoylation on IFITM5 for the Interaction with FKBP11 in Osteoblast Cells. PLoS ONE. 8 [9] (2013) e75831 10.1371/journal.pone.0075831
  5. Song Chen, Huijie Zhang, Shanmugavel Chinnathambi, Nobutaka Hanagata. Synthesis of novel chitosan–silica/CpG oligodeoxynucleotide nanohybrids with enhanced delivery efficiency. Materials Science and Engineering: C. 33 [6] (2013) 3382-3388 10.1016/j.msec.2013.04.017
  6. Song Chen, Xuetao Shi, Shanmugavel Chinnathambi, Nobutaka Hanagata. Large-Scale Fabrication of Free-Standing, Micropatterned Silica Nanotubes Via a Hybrid Hydrogel-Templated Route. Advanced Healthcare Materials. 2 [8] (2013) 1091-1095 10.1002/adhm.201200374
  7. Xia Li, Chunyi Zhi, Nobutaka Hanagata, Maho Yamaguchi, Yoshio Bando, Dmitri Golberg. Boron nitride nanotubes functionalized with mesoporous silica for intracellular delivery of chemotherapy drugs. Chemical Communications. 49 [66] (2013) 7337 10.1039/c3cc42743a
  8. HANAGATA, Nobutaka. Biological Interpretation of the In Vitro Assessment of Nanotoxicity. NANO BIOMEDICINE. 5 [1] (2013) 1-10
  9. 花方 信孝. TLR9を介したCpG誘導サイトカインのナノ粒子によるスイッチング. アレルギーの臨床. 33 [444] (2013) 87-91
  10. 花方 信孝. 免疫を活性化するDNA医薬のナノ粒子による作用制御. バイオインダストリー. 30 [6] (2013) 18-26
  11. Nobutaka Hanagata, Huijie Zhang, Chen, Zhi, Yamazaki. Chitosan-coated boron nitride nanospheres enhance delivery of CpG oligodeoxynucleotides and induction of cytokines. International Journal of Nanomedicine. (2013) 1783 10.2147/ijn.s43251
  12. Mingsheng Xu, Jie Li, Nobutaka Hanagata, Huanxing Su, Hongzheng Chen, Daisuke Fujita. Challenge to assess the toxic contribution of metal cation released from nanomaterials for nanotoxicology – the case of ZnO nanoparticles. Nanoscale. 5 [11] (2013) 4763 10.1039/c3nr34251d
  13. Tatsuyuki Takadate, Tohru Onogawa, Tetsuya Fukuda, Fuyuhiko Motoi, Takashi Suzuki, Kiyonaga Fujii, Makoto Kihara, Sayaka Mikami, Yasuhiko Bando, Shimpei Maeda, Kazuyuki Ishida, Takashi Minowa, Nobutaka Hanagata, Hideo Ohtsuka, Yu Katayose, Shinichi Egawa, Toshihide Nishimura, Michiaki Unno. Novel prognostic protein markers of resectable pancreatic cancer identified by coupled shotgun and targeted proteomics using formalin-fixed paraffin-embedded tissues. International Journal of Cancer. 132 [6] (2013) 1368-1382 10.1002/ijc.27797
  14. Jianhua Zhang, Yufang Zhu, Jie Li, Min Zhu, Cuilian Tao, Nobutaka Hanagata. Preparation and characterization of multifunctional magnetic mesoporous calcium silicate materials. Science and Technology of Advanced Materials. 14 [5] (2013) 055009 10.1088/1468-6996/14/5/055009
  15. Kota Shiba, Motohiro Tagaya, Richard D Tilley, Nobutaka Hanagata. Oxide-based inorganic/organic and nanoporous spherical particles: synthesis and functional properties. Science and Technology of Advanced Materials. 14 [2] (2013) 023002 10.1088/1468-6996/14/2/023002
  16. Song Chen, Xuetao Shi, Shanmugavel Chinnathambi, Hongkai Wu, Nobutaka Hanagata. Generation of microgrooved silica nanotube membranes with sustained drug delivery and cell contact guidance ability by using a Teflon microfluidic chip. Science and Technology of Advanced Materials. 14 [1] (2013) 015005 10.1088/1468-6996/14/1/015005
  17. Yufang Zhu, Fangjian Shang, Bo Li, Yu Dong, Yunfei Liu, Martin R. Lohe, Nobutaka Hanagata, Stefan Kaskel. Magnetic mesoporous bioactive glass scaffolds: preparation, physicochemistry and biological properties. Journal of Materials Chemistry B. 1 [9] (2013) 1279 10.1039/c2tb00262k
  18. Xuefei Li, Liming Xu, Anliang Shao, Gang Wu, Nobutaka Hanagata. Cytotoxic and Genotoxic Effects of Silver Nanoparticles on Primary Syrian Hamster Embryo (SHE) Cells. Journal of Nanoscience and Nanotechnology. 13 [1] (2013) 161-170 10.1166/jnn.2013.7077
  19. Suwarti Suwarti, Tomohiko Yamazaki, Chechetka Svetlana, Nobutaka Hanagata. Recognition of CpG oligodeoxynucleotides by human Toll-like receptor 9 and subsequent cytokine induction. Biochemical and Biophysical Research Communications. 430 [4] (2013) 1234-1239 10.1016/j.bbrc.2012.12.068
  20. Song Chen, Nobutaka Hanagata. Directing Osteoblast Alignment and Elongation on the Micro-Grooved Silica-Based Hybrid Membrane. Advanced Materials Research. 647 (2013) 165-169 10.4028/www.scientific.net/amr.647.165
2012
  1. ZHUANG, Fei, HANAGATA, Nobutaka. Synergic Toxicity of Solid Particles and Released Zinc from Zinc Oxide Nanoparticles to Human Lung Epithelial Cells. NANO BIOMEDICINE. 4 [2] (2012) 90-112
  2. Mingsheng Xu, Jie Li, Hideo Iwai, Qingsong Mei, Daisuke Fujita, Huanxing Su, Hongzheng Chen, Nobutaka Hanagata. Formation of Nano-Bio-Complex as Nanomaterials Dispersed in a Biological Solution for Understanding Nanobiological Interactions. Scientific Reports. 2 [1] (2012) 10.1038/srep00406
  3. Shanmugavel Chinnathambi, Song Chen, Singaravelu Ganesan, Nobutaka Hanagata. Binding Mode of CpG Oligodeoxynucleotides to Nanoparticles Regulates Bifurcated Cytokine induction via Toll-like Receptor 9. Scientific Reports. 2 [1] (2012) 10.1038/srep00534
  4. Motohiro Tagaya, Nobutaka Hanagata, Takaomi Kobayashi. Templating Effect of Mesostructured Surfactant–Silica Monolithic Films on the Surface Structural and Mechanical Properties. ACS Applied Materials & Interfaces. 4 [11] (2012) 6169-6175 10.1021/am301789v
  5. Motohiro Tagaya, Nobutaka Hanagata, Toshiyuki Ikoma, Takaomi Kobayashi, Kota Shiba, Tomohiko Yoshioka, Junzo Tnaka. Cytotoxicity and Cancer Detection Ability of the Luminescent Nanoporous Silica Spheres Immobilized with Folic Acid Derivative. Key Engineering Materials. 529-530 (2012) 630-635 10.4028/www.scientific.net/kem.529-530.630
  6. Yuki SHIROSAKI, Hiroki YOSHIHARA, Song CHEN, Mark BLEVINS, Yuri NAKAMURA, Nobutaka HANAGATA, Satoshi HAYAKAWA, Artemis STAMBOULIS, Akiyoshi OSAKA. Electrospun poly(vinyl alcohol) as a template of silica hollow and solid micro-fibrous mats. Journal of the Ceramic Society of Japan. 120 [1407] (2012) 520-524 10.2109/jcersj2.120.520
  7. Song Chen, Shanmugavel Chinnathambi, Xuetao Shi, Akiyoshi Osaka, Yufang Zhu, Nobutaka Hanagata. Fabrication of novel collagen-silica hybrid membranes with tailored biodegradation and strong cell contact guidance ability. Journal of Materials Chemistry. 22 [41] (2012) 21885 10.1039/c2jm35383k
  8. Huijie Zhang, Tomohiko Yamazaki, Chunyi Zhi, Nobutaka Hanagata. Identification of a boron nitride nanosphere-binding peptide for the intracellular delivery of CpG oligodeoxynucleotides. Nanoscale. 4 [20] (2012) 6343 10.1039/c2nr31189e
  9. 田沼 繁夫, 福島 整, 竹口 雅樹, 坂田 修身, 熊倉 浩明, 花方 信孝, 箕輪 貴司. 物質・材料研究機構中核機能部門における計測・分析・解析技術. 工業材料. 60 [8] (2012) 18-23
  10. Qingmin Ji, Tomohiko Yamazaki, Nobutaka Hanagata, Michael V. Lee, Jonathan P. Hill, Katsuhiko Ariga. Silica-based gene reverse transfection: an upright nanosheet network for promoted DNA delivery to cells. Chemical Communications. 48 [68] (2012) 8496 10.1039/c2cc34289h
  11. Nobutaka Hanagata, Manoharan, Qingmin Ji, Yamazaki, Shanmugavel, Chen, Ganesan, Hill, Ariga. Effect of molecular weight of polyethyleneimine on loading of CpG oligodeoxynucleotides onto flake-shell silica nanoparticles for enhanced TLR9-mediated induction of interferon-α. International Journal of Nanomedicine. (2012) 3625 10.2147/ijn.s32592
  12. TAGAYAMotohiro, TANAKAJunzo, HANAGATA, Nobutaka, IKOMAToshiyuki, TAKEMURA, Taro, SHIBA, Kota, KOBAYASHITakaomi. In Vitro Targeting of Cancer Cells with Luminescent Nanoporous Silica Spheres. TRANSACTIONS ON GIGAKU. e-journal 1 [1] (2012) 01014-1-01014-8
  13. Tatsuyuki Takadate, Tohru Onogawa, Kiyonaga Fujii, Fuyuhiko Motoi, Sayaka Mikami, Tetsuya Fukuda, Makoto Kihara, Takashi Suzuki, Taro Takemura, Takashi Minowa, Nobutaka Hanagata, Kengo Kinoshita, Takanori Morikawa, Keiichi Shirasaki, Toshiki Rikiyama, Yu Katayose, Shinichi Egawa, Toshihide Nishimura, Michiaki Unno. Nm23/nucleoside diphosphate kinase-A as a potent prognostic marker in invasive pancreatic ductal carcinoma identified by proteomic analysis of laser micro-dissected formalin-fixed paraffin-embedded tissue. Clinical Proteomics. 9 [1] (2012) 8 10.1186/1559-0275-9-8
  14. Ling Zhang, Yoshihisa Kaizuka, Nobutaka Hanagata. Imaging of Fas–FasL membrane microdomains during apoptosis in a reconstituted cell–cell junction. Biochemical and Biophysical Research Communications. 422 [2] (2012) 298-304 10.1016/j.bbrc.2012.04.152
  15. Liming Xu, Xuefei Li, Taro Takemura, Nobutaka Hanagata, Gang Wu, Laisheng Chou. Genotoxicity and molecular response of silver nanoparticle (NP)-based hydrogel. Journal of Nanobiotechnology. 10 [1] (2012) 16 10.1186/1477-3155-10-16
  16. Nobutaka Hanagata. Structure-dependent immunostimulatory effect of CpG oligodeoxynucleotides and their delivery system. International Journal of Nanomedicine. (2012) 2181 10.2147/ijn.s30197
  17. Motohiro Tagaya, Toshiyuki Ikoma, Nobutaka Hanagata, Junzo Tanaka. Analytical Investigation of Protein Mediation Between Biomaterials and Cells. Materials Express. 2 [1] (2012) 1-22 10.1166/mex.2012.1053
  18. Y. Hagiwara, A. Ando, Y. Onoda, T. Takemura, T. Minowa, N. Hanagata, M. Tsuchiya, T. Watanabe, E. Chimoto, H. Suda, N. Takahashi, H. Sugaya, Y. Saijo, E. Itoi. Coexistence of fibrotic and chondrogenic process in the capsule of idiopathic frozen shoulders. Osteoarthritis and Cartilage. 20 [3] (2012) 241-249 10.1016/j.joca.2011.12.008
  19. Sachiko Yoshie, Masateru Ikehata, Noriyuki Hirota, Taro Takemura, Takashi Minowa, Nobutaka Hanagata, Toshio Hayakawa. Evaluation of mutagenicity and co-mutagenicity of strong static magnetic fields up to 13 Tesla in Escherichia coli deficient in superoxide dismutase. Journal of Magnetic Resonance Imaging. 35 [3] (2012) 731-736 10.1002/jmri.22883
  20. Dohiko Terada, Hisatoshi Kobayashi, Kun Zhang, Ashutosh Tiwari, Chiaki Yoshikawa, Nobutaka Hanagata. Transient charge-masking effect of applied voltage on electrospinning of pure chitosan nanofibers from aqueous solutions. Science and Technology of Advanced Materials. 13 [1] (2012) 015003 10.1088/1468-6996/13/1/015003
2011
  1. Nobutaka Hanagata, Fei Zhuang, Sarah Connolly, Jie Li, Nobuhiro Ogawa, Mingsheng Xu. Molecular Responses of Human Lung Epithelial Cells to the Toxicity of Copper Oxide Nanoparticles Inferred from Whole Genome Expression Analysis. ACS Nano. 5 [12] (2011) 9326-9338 10.1021/nn203728t
  2. Song Chen, Xuetao Shi, Hiromi Morita, Jie Li, Nobuhiro Ogawa, Toshiyuki Ikoma, Satoshi Hayakawa, Yuki Shirosaki, Akiyoshi Osaka, Nobutaka Hanagata. BMP-2-loaded silica nanotube fibrous meshes for bone generation. Science and Technology of Advanced Materials. 12 [6] (2011) 065003 10.1088/1468-6996/12/6/065003
  3. Motohiro Tagaya, Toshiyuki Ikoma, Masaki Takeguchi, Nobutaka Hanagata, Junzo Tanaka. Interfacial Serum Protein Effect on Biological Apatite Growth. The Journal of Physical Chemistry C. 115 [45] (2011) 22523-22533 10.1021/jp208104z
  4. Motohiro Tagaya, Toshiyuki Ikoma, Taro Takemura, Nobutaka Hanagata, Tomohiko Yoshioka, Junzo Tanaka. Protein Adsorption and Subsequent Fibroblasts Adhesion on Hydroxyapatite Nanocrystals. IOP Conference Series: Materials Science and Engineering. 18 [19] (2011) 192009 10.1088/1757-899x/18/19/192009
  5. Wenjun Meng, Tomohiko Yamazaki, Yuuki Nishida, Nobutaka Hanagata. Nuclease-resistant immunostimulatory phosphodiester CpG oligodeoxynucleotides as human Toll-like receptor 9 agonists. BMC Biotechnology. 11 [1] (2011) 88 10.1186/1472-6750-11-88
  6. Yufang Zhu, Wenjun Meng, Nobutaka Hanagata. Cytosine-phosphodiester-guanine oligodeoxynucleotide (CpG ODN)-capped hollow mesoporous silica particles for enzyme-triggered drug delivery. Dalton Transactions. 40 [39] (2011) 10203 10.1039/c1dt11114k
  7. Chunyi Zhi, Nobutaka Hanagata, Yoshio Bando, Dmitri Golberg. Dispersible Shortened Boron Nitride Nanotubes with Improved Molecule-Loading Capacity. Chemistry - An Asian Journal. 6 [9] (2011) 2530-2535 10.1002/asia.201100114
  8. Mitsuhiro Okuda, Nobuhiro Ogawa, Masaki Takeguchi, Ayako Hashimoto, Motohiro Tagaya, Song Chen, Nobutaka Hanagata, Toshiyuki Ikoma. Minerals and Aligned Collagen Fibrils in Tilapia Fish Scales: Structural Analysis Using Dark-Field and Energy-Filtered Transmission Electron Microscopy and Electron Tomography. Microscopy and Microanalysis. 17 [05] (2011) 788-798 10.1017/s1431927611011949
  9. Motohiro Tagaya, Tomohiko Yamazaki, Daiji Tsuya, Yoshimasa Sugimoto, Nobutaka Hanagata, Toshiyuki Ikoma. Nano/Microstructural Effect of Hydroxyapatite Nanocrystals on Hepatocyte Cell Aggregation and Adhesion. Macromolecular Bioscience. (2011) n/a-n/a 10.1002/mabi.201100182
  10. Satoshi Migita, Nobutaka Hanagata, Daiju Tsuya, Tomohiko Yamazaki, Yoshimasa Sugimoto, Toshiyuki Ikoma. Transfection efficiency for size-separated cells synchronized in cell cycle by microfluidic device. Biomedical Microdevices. 13 [4] (2011) 725-729 10.1007/s10544-011-9542-6
  11. Yufang Zhu, Wenjun Meng, Hong Gao, Nobutaka Hanagata. Hollow Mesoporous Silica/Poly(l-lysine) Particles for Codelivery of Drug and Gene with Enzyme-Triggered Release Property. The Journal of Physical Chemistry C. 115 [28] (2011) 13630-13636 10.1021/jp203454g
  12. Motohiro Tagaya, Toshiyuki Ikoma, Taro Takemura, Nobutaka Hanagata, Mitsuhiro Okuda, Tomohiko Yoshioka, Junzo Tanaka. Detection of Interfacial Phenomena with Osteoblast-like Cell Adhesion on Hydroxyapatite and Oxidized Polystyrene by the Quartz Crystal Microbalance with Dissipation. Langmuir. 27 [12] (2011) 7635-7644 10.1021/la200008z
  13. Motohiro Tagaya, Toshiyuki Ikoma, Taro Takemura, Nobutaka Hanagata, Tomohiko Yoshioka, Junzo Tanaka. Effect of Interfacial Proteins on Osteoblast-like Cell Adhesion to Hydroxyapatite Nanocrystals. Langmuir. 27 [12] (2011) 7645-7653 10.1021/la200621p
  14. Song Chen, Akiyoshi Osaka, Toshiyuki Ikoma, Hiromi Morita, Jie Li, Masaki Takeguchi, Nobutaka Hanagata. Fabrication, microstructure, and BMP-2 delivery of novel biodegradable and biocompatible silicate–collagen hybrid fibril sheets. Journal of Materials Chemistry. 21 [29] (2011) 10942 10.1039/c1jm10829h
  15. Nobutaka Hanagata, Xianglan Li. Osteoblast-enriched membrane protein IFITM5 regulates the association of CD9 with an FKBP11–CD81–FPRP complex and stimulates expression of interferon-induced genes. Biochemical and Biophysical Research Communications. 409 [3] (2011) 378-384 10.1016/j.bbrc.2011.04.136
  16. Motohiro Tagaya, Toshiyuki Ikoma, Nobutaka Hanagata, Tomohiko Yoshioka, Junzo Tanaka. Competitive adsorption of fibronectin and albumin on hydroxyapatite nanocrystals. Science and Technology of Advanced Materials. 12 [3] (2011) 034411 10.1088/1468-6996/12/3/034411
  17. Mingsheng Xu, Daisuke Fujita, Hongzheng Chen, Nobutaka Hanagata. Formation of monolayer and few-layer hexagonal boron nitride nanosheets via surface segregation. Nanoscale. 3 [7] (2011) 2854 10.1039/c1nr10294j
  18. Yufang Zhu, Xianglan Li, Junhe Yang, Shulin Wang, Hong Gao, Nobutaka Hanagata. Composition–structure–property relationships of the CaO–MxOy–SiO2–P2O5 (M = Zr, Mg, Sr) mesoporous bioactive glass (MBG) scaffolds. Journal of Materials Chemistry. 21 [25] (2011) 9208 10.1039/c1jm10838g
  19. Motohiro Tagaya, Tomohiko Yamazaki, Satoshi Migita, Nobutaka Hanagata, Toshiyuki Ikoma. Hepatocyte Adhesion Behavior on Modified Hydroxyapatite Nanocrystals with Quartz Crystal Microbalance. Bioceramics Development and Applications. 1 (2011) 1-4 10.4303/bda/d110157
  20. Motohiro Tagaya, Toshiyuki Ikoma, Taro Takemura, Satoshi Migita, Mitsuhiro Okuda, Tomohiko Yoshioka, Nobutaka Hanagata, Junzo Tanaka. Initial Adhesion Behavior of Fibroblasts onto Hydroxyapatite Nanocrystals. Bioceramics Development and Applications. 1 (2011) 1-4 10.4303/bda/d110165
  21. Nobutaka Hanagata, Xianglan Li, Hiromi Morita, Taro Takemura, Jie Li, Takashi Minowa. Characterization of the osteoblast-specific transmembrane protein IFITM5 and analysis of IFITM5-deficient mice. Journal of Bone and Mineral Metabolism. 29 [3] (2011) 279-290 10.1007/s00774-010-0221-0
  22. Chunyi Zhi, Wenjun Meng, Tomohiko Yamazaki, Yoshio Bando, Dmitri Golberg, Chengchun Tang, Nobutaka Hanagata. BN nanospheres as CpG ODN carriers for activation of toll-like receptor 9. Journal of Materials Chemistry. 21 [14] (2011) 5219 10.1039/c1jm10199d
  23. Liming Xu, Taro Takemura, Mingshen Xu, Nobutaka Hanagata. Toxicity of Silver Nanoparticles as Assessed by Global Gene Expression Analysis. Materials Express. 1 [1] (2011) 74-79 10.1166/mex.2011.1010
  24. Mingsheng Xu, Daisuke Fujita, Keisuke Sagisaka, Eiichiro Watanabe, Nobutaka Hanagata. Production of Extended Single-Layer Graphene. ACS Nano. 5 [2] (2011) 1522-1528 10.1021/nn103428k
  25. Song Chen, Akiyoshi Osaka, Nobutaka Hanagata. Collagen-templated sol–gel fabrication, microstructure, in vitro apatite deposition, and osteoblastic cell MC3T3-E1 compatibility of novel silica nanotube compacts. Journal of Materials Chemistry. 21 [12] (2011) 4332 10.1039/c0jm03823g
  26. S. Chen, N. Hirota, M. Okuda, M. Takeguchi, H. Kobayashi, N. Hanagata, T. Ikoma. Microstructures and rheological properties of tilapia fish-scale collagen hydrogels with aligned fibrils fabricated under magnetic fields. Acta Biomaterialia. 7 [2] (2011) 644-652 10.1016/j.actbio.2010.09.014
  27. Yufang Zhu, Wenjun Meng, Xianglan Li, Hong Gao, Nobutaka Hanagata. Design of Mesoporous Silica/Cytosine−Phosphodiester−Guanine Oligodeoxynucleotide Complexes To Enhance Delivery Efficiency. The Journal of Physical Chemistry C. 115 [2] (2011) 447-452 10.1021/jp109535d
  28. M. Grandcolas, J. Ye, N. Hanagata. Combination of photocatalytic and antibacterial effects of silver oxide loaded on titania nanotubes. Materials Letters. 65 [2] (2011) 236-239 10.1016/j.matlet.2010.08.082
2010
  1. Mingsheng Xu, Daisuke Fujita, Shoko Kajiwara, Takashi Minowa, Xianglan Li, Taro Takemura, Hideo Iwai, Nobutaka Hanagata. Contribution of physicochemical characteristics of nano-oxides to cytotoxicity. Biomaterials. 31 [31] (2010) 8022-8031 10.1016/j.biomaterials.2010.06.022
  2. Motohiro Tagaya, Toshiyuki Ikoma, Satoshi Migita, Mitsuhiro Okuda, Taro Takemura, Nobutaka Hanagata, Tomohiko Yoshioka, Junzo Tanaka. Fetal bovine serum adsorption onto hydroxyapatite sensor monitoring by quartz crystal microbalance with dissipation technique. Materials Science and Engineering: B. 173 [1-3] (2010) 176-181 10.1016/j.mseb.2010.01.034
  3. Mitsuhiro Okuda, Masaki Takeguchi, Yufang Zhu, Ayako Hashimoto, Nobuhiro Ogawa, Motohiro Tagaya, Song Chen, Nobutaka Hanagata, Toshiyuki Ikoma. Structural analysis of rattle-type hollow mesoporous silica spheres using electron tomography and energy filtered imaging. Surface and Interface Analysis. 42 [10-11] (2010) 1548-1551 10.1002/sia.3572
  4. Toru Tonegawa, Toshiyuki Ikoma, Yasushi Suetsugu, Naoki Igawa, Yoshitaka Matsushita, Tomohiko Yoshioka, Nobutaka Hanagata, Junzo Tanaka. Thermal expansion of type A carbonate apatite. Materials Science and Engineering: B. 173 [1-3] (2010) 171-175 10.1016/j.mseb.2010.02.008
  5. Mingsheng Xu, Daisuke Fujita, Nobutaka Hanagata. Monitoring electron-beam irradiation effects on graphenes by temporal Auger electron spectroscopy. Nanotechnology. 21 [26] (2010) 265705 10.1088/0957-4484/21/26/265705
  6. Mingsheng Xu, Daisuke Fujita, Jianhua Gao, Nobutaka Hanagata. Auger Electron Spectroscopy: A Rational Method for Determining Thickness of Graphene Films. ACS Nano. 4 [5] (2010) 2937-2945 10.1021/nn100276w
  7. Toru Tonegawa, Toshiyuki Ikoma, Tomohiko Yoshioka, Nobutaka Hanagata, Junzo Tanaka. Crystal structure refinement of A-type carbonate apatite by X-ray powder diffraction. Journal of Materials Science. 45 [9] (2010) 2419-2426 10.1007/s10853-010-4209-x
  8. 花方 信孝. バイオセラミックスのマテリアルゲノミクス解析. バイオマテリアル. 28 [2] (2010) 116-123
  9. M. Okuda, M. Takeguchi, O. O Ruairc, M. Tagaya, Y. Zhu, A. Hashimoto, N. Hanagata, W. Schmitt, T. Ikoma. Structural analysis of hydroxyapatite coating on magnetite nanoparticles using energy filter imaging and electron tomography. Journal of Electron Microscopy. 59 [2] (2010) 173-179 10.1093/jmicro/dfp055
  10. Satoshi Migita, Kei Funakoshi, Daiju Tsuya, Tomohiko Yamazaki, Akiyoshi Taniguchi, Yoshimasa Sugimoto, Nobutaka Hanagata, Toshiyuki Ikoma. Cell cycle and size sorting of mammalian cells using a microfluidic device. Analytical Methods. 2 [6] (2010) 657 10.1039/c0ay00039f
  11. Yufang Zhu, Toshiyuki Ikoma, Nobutaka Hanagata, Stefan Kaskel. Rattle-Type Fe3O4@SiO2Hollow Mesoporous Spheres as Carriers for Drug Delivery. Small. 6 [3] (2010) 471-478 10.1002/smll.200901403
  12. Motohiro Tagaya, Toshiyuki Ikoma, Nobutaka Hanagata, Dinko Chakarov, Bengt Kasemo, Junzo Tanaka. Reusable hydroxyapatite nanocrystal sensors for protein adsorption. Science and Technology of Advanced Materials. 11 [4] (2010) 045002 10.1088/1468-6996/11/4/045002
  13. HANAGATA, Nobutaka, XU, Mingsheng, TAKEMURA, Taro, zhuang fei. Cellular Response to ZnO Nanoparticle Toxicity Inferred from Global Gene Expression Profiles. NANO BIOMEDICINE. 2 [2] (2010) 153-169
  14. Nobutaka Hanagata, Taro Takemura, Takashi Minowa. Global gene expression analysis for evaluation and design of biomaterials. Science and Technology of Advanced Materials. 11 [1] (2010) 013001 10.1088/1468-6996/11/1/013001
  15. Song Chen, Toshiyuki Ikoma, Nobuhiro Ogawa, Satoshi Migita, Hisatoshi Kobayashi, Nobutaka Hanagata. In vitroformation and thermal transition of novel hybrid fibrils from type I fish scale collagen and type I porcine collagen. Science and Technology of Advanced Materials. 11 [3] (2010) 035001 10.1088/1468-6996/11/3/035001
2009
  1. Mingsheng Xu, Daisuke Fujita, Nobutaka Hanagata. Perspectives and Challenges of Emerging Single-Molecule DNA Sequencing Technologies. Small. 5 [23] (2009) 2638-2649 10.1002/smll.200900976
  2. Mitsuhiro Okuda, Masaki Takeguchi, Motohiro Tagaya, Toru Tonegawa, Ayako Hashimoto, Nobutaka Hanagata, Toshiyuki Ikoma. Elemental distribution analysis of type I collagen fibrils in tilapia fish scale with energy-filtered transmission electron microscope. Micron. 40 [5-6] (2009) 665-668 10.1016/j.micron.2009.04.001
  3. Seiya Yamayoshi, Yasuko Yamashita, Jifen Li, Nobutaka Hanagata, Takashi Minowa, Taro Takemura, Satoshi Koike. Scavenger receptor B2 is a cellular receptor for enterovirus 71. Nature Medicine. 15 [7] (2009) 798-801 10.1038/nm.1992
  4. Yufang Zhu, Stefan Kaskel, Toshiyuki Ikoma, Nobutaka Hanagata. Magnetic SBA-15/poly(N-isopropylacrylamide) composite: Preparation, characterization and temperature-responsive drug release property. Microporous and Mesoporous Materials. 123 [1-3] (2009) 107-112 10.1016/j.micromeso.2009.03.031
  5. Yufang Zhu, Emanuel Kockrick, Toshiyuki Ikoma, Nobutaka Hanagata, Stefan Kaskel. An Efficient Route to Rattle-Type Fe3O4@SiO2Hollow Mesoporous Spheres Using Colloidal Carbon Spheres Templates. Chemistry of Materials. 21 [12] (2009) 2547-2553 10.1021/cm900956j
  6. Toshiyuki Ikoma, Motohiro Tagaya, Nobutaka Hanagata, Tomohiko Yoshioka, Dinko Chakarov, Bengt Kasemo, Junzo Tanaka. Protein Adsorption on Hydroxyapatite Nanosensors with Different Crystal Sizes StudiedIn Situby a Quartz Crystal Microbalance with the Dissipation Method. Journal of the American Ceramic Society. 92 [5] (2009) 1125-1128 10.1111/j.1551-2916.2009.02957.x
  7. Yufang Zhu, Emanuel Kockrick, Stefan Kaskel, Toshiyuki Ikoma, Nobutaka Hanagata. Nanocasting Route to Ordered Mesoporous Carbon with FePt Nanoparticles and Its Phenol Adsorption Property. The Journal of Physical Chemistry C. 113 [15] (2009) 5998-6002 10.1021/jp8105309
  8. Lingli Zhang, Nobutaka Hanagata, Megumi Maeda, Takashi Minowa, Toshiyuki Ikoma, Hongsong Fan, Xingdong Zhang. Porous hydroxyapatite and biphasic calcium phosphate ceramics promote ectopic osteoblast differentiation from mesenchymal stem cells. Science and Technology of Advanced Materials. 10 [2] (2009) 025003 10.1088/1468-6996/10/2/025003
2008
  1. 大熊恒雄, 清水恭子, 渡邉和彦, 箕輪 貴司, 花方 信孝. 産官学が連携して開発した「キトサン・ナノ繊維を用いた細胞培養基材」. WEB JOURNAL. 92 (2008) 38-41
  2. 小暮亮雅, 粉川良平, 藤井岳直, 紋川 亮, 生駒 俊之, 竹村 太郎, 花方 信孝, 田中 順三. ナノサーチ顕微鏡による細胞外マトリックスの観察. 島津評論(Shimadzu Review). 64 [3.4] (2008) 131-137
2007
  1. Nobutaka Hanagata, Taro Takemura, Akira Monkawa, Toshiyuki Ikoma, Junzo Tanaka. Phenotype and gene expression pattern of osteoblast-like cells cultured on polystyrene and hydroxyapatite with pre-adsorbed type-I collagen. Journal of Biomedical Materials Research Part A. 83A [2] (2007) 362-371 10.1002/jbm.a.31240
  2. 花方 信孝. 網羅的遺伝子発現解析による生体材料のin vitro評価. MATERIALS INTEGRATION(マテリアルインテグレーション). 20 [11] (2007) 101-106
  3. Miyama Masashi, HANAGATA, Nobutaka. Microarray gene expression profiling for salt tolerance gene selection. Plant Stress. 1 [1] (2007) 118-122
  4. Masashi Miyama, Nobutaka Hanagata. Microarray analysis of 7029 gene expression patterns in burma mangrove under high-salinity stress. Plant Science. 172 [5] (2007) 948-957 10.1016/j.plantsci.2007.01.004
  5. 川上 亘作, 生駒 俊之, 田口 哲志, 谷口 彰良, 陳 国平, 花方 信孝, 内田 義之, 立石 哲也. 次世代DDS型治療システム創成に向けた取り組み. WEB Journal. 84 (2007) 35-38
2006
  1. Nobutaka Hanagata, Taro Takemura, Akira Monkawa, Toshiyuki Ikoma, Junzo Tanaka. Pre-adsorbed type-I collagen structure-dependent changes in osteoblastic phenotype. Biochemical and Biophysical Research Communications. 344 [4] (2006) 1234-1240 10.1016/j.bbrc.2006.04.021
  2. Satoshi Sasaki, Yosuke Chiba, Nobutaka Hanagata. Responses of Bruguiera gymnorrhiza to saltwater monitored by miniature electrodes. Bioelectrochemistry. 68 [2] (2006) 202-205 10.1016/j.bioelechem.2005.06.002

書籍 TSV

2015
  1. 生駒俊之, 田中 順三, 伊藤 博, 芹澤 武, 早乙女 進一, 花方 信孝, 吉岡 朋彦, 澤田 敏樹, 多賀谷 基博. 生物材料・ナノ材料に対する細胞の遺伝子応答. ナノバイオとナノメディシン. 2015 , 204-245
  2. 花方 信孝. ナノイムノセラピー. 2015 , 1-208
2014
  1. Mingsheng Xu, FUJITA, Daisuke, Huanxing Su, Hongzheng Chen, HANAGATA, Nobutaka. Analytical Characterization of Nanomaterials in Biological Matrices for Hazard Assessment. Biointeractinos of Nanomaterials. 2014 , 159-174
  2. Song Chen, Satoshi Hayakawa, Yuki Shirosaki, Nobutaka Hanagata, Akiyoshi Osaka. Biomedical Applications of Sol-Gel Nanocomposites. Sol-Gel Nanocomposites. Springer New York 2014 , 167-190 10.1007/978-1-4939-1209-4_7
2012
  1. 花方 信孝. DNAマイクロアレイ. 先端バイオマテリアルハンドブック. 2012 , 159-164

会議録 TSV

2018
  1. CHINNATHAMBI, Shanmugavel, Subramani Karthikeyan, Mangaiyarkarsi Rajendiran, Kanniyappan Udayakumar, Arunkumar Manoharan, Saravanan Kandasamy, HANAGATA, Nobutaka. 4-Hydroxycoumarin Derivative: N-(diphenylmethyl)-2-[(2-oxo-2H-chromen-4-yl)oxy]acetamide Interaction with Human Serum Albumin. JOURNAL OF SPECTROSCOPY. 2018, 3480384-1-3480384-14
2012
  1. Motohiro Tagaya, Nobutaka Hanagata, Toshiyuki Ikoma, Takaomi Kobayashi, Kota Shiba, Tomohiko Yoshioka, Junzo Tnaka. Cytotoxicity and Cancer Detection Ability of the Luminescent Nanoporous Silica Spheres Immobilized with Folic Acid Derivative. KEY ENGINEERING MATERIALS. 2012, 630-635
2011
  1. Motohiro Tagaya, Toshiyuki Ikoma, Taro Takemura, Nobutaka Hanagata, Tomohiko Yoshioka, Junzo Tanaka. Protein Adsorption and Subsequent Fibroblasts Adhesion on Hydroxyapatite Nanocrystals. IOP CONF. SERIES : MATERIALS SCIENCE AND ENGINEERING. 2011, 192009-1-192009-4
2009
  1. LI, Yaqi, HIROTA, Noriyuki, OKUDA, Mitsuhiro, CHEN, Song, TAGAYA, Motohiro, Yuki Shirosaki, Satoshi Hayakawa, Akiyoshi Osaka, HANAGATA, Nobutaka, IKOMA, Toshiyuki. Viscoelastic property of collagen gels with aligned fibril structure. BIOCERAMICS 22(2009). 2009, 661-664
  2. Toru Tonegawa, IKOMA, Toshiyuki, SUETSUGU, Yasushi, Naoki Igawa, MATSUSHITA, Yoshitaka, Tomohiko Yoshioka, HANAGATA, Nobutaka, Junzo Tanaka. Crystal structure of high purity type A carbonate apatite. Bioceramics22(2009). 2009, 93-96
  3. OKUDA, Mitsuhiro, TAKEGUCHI, Masaki, ZHU, Yufang, HASHIMOTO, Ayako, TAGAYA, Motohiro, HANAGATA, Nobutaka, IKOMA, Toshiyuki. Structural Analysis of Rattle-type Hollow Mesoporous Spheres using Electron Tomography and Energy Filter Imagin. Proceedings of International Symposium on Atomic Level Characterizations. 2009, 259-261
  4. TAGAYA, Motohiro, IKOMA, Toshiyuki, TAKEMURA, Taro, MIGITA, Satoshi, OKUDA, Mitsuhiro, tomohiko yoshioka, HANAGATA, Nobutaka, junzo tanak. Initial adhesion behavior of fibroblasts onto hydroxyapatite nanocrystals. Bioceramics22(2009). 2009, 439-442
  5. TAGAYA, Motohiro, YAMAZAKI, Tomohiko, MIGITA, Satoshi, HANAGATA, Nobutaka, IKOMA, Toshiyuki. Hepatocyte adhesion behavior on modified hydroxyapatite nanocrystals with quartz crystal microbalance. Bioceramis22(2009). 2009, 407-410
2008
  1. TONEGAWA, Toru, IKOMA, Toshiyuki, YOSHIOKA Tomohiko, SHINOZAKI Kazuo, HANAGATA, Nobutaka, TANAKA, Junzo. Adsorption and Sustained Release of Insulin from Zinc Hydroxyapatite Microparticle with Poly(Lactic acid)Coating. KEY ENGINEERING MATERIALS. 2008, 507-510
  2. IKOMA, Toshiyuki, TAGAYA, Motohiro, TONEGAWA, Toru, OKUDA, Mitsuhiro, HANAGATA, Nobutaka, Tomohiko Yoshioka, Dinko Chakarov, Bengt Kasemo, TANAKA Junzo. The Surface Property of Hydroxyapatite: Sensing with Quartz Crystal Microbalance. KEY ENGINEERING MATERIALS. 2008, 89-92
  3. TAGAYA, Motohiro, IKOMA, Toshiyuki, TAKEMURA, Taro, OKUDA, Mitsuhiro, HANAGATA, Nobutaka, T.Yoshioka, D.Chakarov, B.Kasemo, J.Tanaka. Adsorption of Proteins Derived from Fetal Bovine Serum onto Hydroxyapatite Nanocrystals with Quartz Crystal Microbalance Techniq. KEY ENGINEERING MATERIALS. 2008, 47-50
2007
  1. TAKEMURA, Taro, IKOMA, Toshiyuki, HANAGATA, Nobutaka. Effect of Acid Treated Hydroxyapatite on Osteoblast Maturation. KEY ENGINEERING MATERIALS. 2007, 1029-1032
  2. TONEGAWA, Toru, IKOMA, Toshiyuki, YOSHIOKA Tomohiko, CHEN, Guoping, HANAGATA, Nobutaka, TANAKA, Junzo. Characterization and Protein Adsorption Ability of Zinc, Iron and Magnesium Hydroxyapatite. KEY ENGINEERING MATERIALS. 2007, 187-190
  3. Yoshioka Tomohiko, IKOMA, Toshiyuki, MONKAWA, Akira, TONEGAWA TORU, Chakarov D, Kasemo B, HANAGATA, Nobutaka, Tanaka Junzo. Protein Adsorption on Hydroxyapatite Nano-crystals with Quartz Crystal Microbalance Technique. KEY ENGINEERING MATERIALS. 2007, 1119-1122
  4. 吉江幸子, 池畑政輝, 早川敏雄, 廣田 憲之, 竹村 太郎, 箕輪 貴司, 花方 信孝. 定常磁場のSOD欠損大腸菌による変異原性評価. 電気学会研究会資料. 2007, 7-10
  5. IKOMA, Toshiyuki, Tomohiko Yoshioka, Satoshi Nakamura , HANAGATA, Nobutaka, Tetuya Abe, Masataka Sakane, Naoyuki Ochiai, Junzo Tanaka. Rigid Hydroxyapatite Alginate Beads for Sustained Release of Paclitaxel . KEY ENGINEERING MATERIALS. 2007, 535-538
  6. TAKEMURA, Taro, Hongsong Fan, IKOMA, Toshiyuki, Junzo Tanaka, HANAGATA, Nobutaka. Gene expression profile of osteoblast-like cells on calcium phosphate biomaterials. Key Engineering Materials. 2007, 1087-1090
2006
  1. TAKEMURA, Taro, MONKAWA, Akira, IKOMA, Toshiyuki, Junzo Tanaka, HANAGATA, Nobutaka. Enhanced expression of the osteoblastic phenotype by hydrochloric acid treated hydroxyapatite. Archives of BioCeramics Research. 2006, 167-170

口頭発表 TSV

2019
  1. HANAGATA, Nobutaka. CpG DNA complexed with calcium phosphate possesses dual characteristics of Th1- and Th2-type vaccine adjuvants. ISNM2019 (13th International Symposium on Nanomedicine). 2019
  2. 渡部 和彦, 加藤陽一郎, 佐久間美帆, 村田麻喜子, 新井田(川口)素子, 竹村 太郎, 花方 信孝, 柿田明美, 柴田亮行. 培養ニューロン細胞質TDP-43凝集体形成を抑制する分子の解析. 第14回日本臨床ストレス応答学会大会. 2019
  3. WANG, Hongxin, ZHANG, Han, GOTO, Kenta, WATANABE, Ikumu, DA, Bo, HANAGATA, Nobutaka, FUJITA, Daisuke, TAMURA, Ryo. High spatial and temporal resolution mapping of active stress on the surface of living material. 2019日本表面真空学会学術講演会. 2019
2016
  1. CHINNATHAMBI, Shanmugavel, HANAGATA, Nobutaka. Superparamagnetic CdSe/ZnS Quantum Dot Micelles for Cancer Cell Imaging. Advanced materials conference 2016, Malaysia. 2016
  2. CHEN, Min-Hua, MINOWA, Takashi, Abigail Magee, LI, Xianglan, TAKEMURA, Taro, HANAGATA, Nobutaka. Apatite Nanoparticles-Assisted Dissolving Microneedles for Transdermal Adjuvant CpG DNA Delivery. Advanced materials conference 2016, Malaysia. 2016
  3. CHEN, Min-Hua, MINOWA, Takashi, LI, Xianglan, TAKEMURA, Taro, HANAGATA, Nobutaka. Dissolving Microneedles As a Transdermal Delivery System for Adjuvant CpG DNA. Advanced materials conference 2016, Malaysia. 2016
  4. YAMAZAKI, Tomohiko, HANAGATA, Nobutaka. Improved immunostimulatory activity of phosphodiester CpG oligodeoxynucleotides by G-quadruplex formation. International Symposium on Nanomedicine. 2016
  5. CHEN, Min-Hua, MINOWA, Takashi, LI, Xianglan, TAKEMURA, Taro, HANAGATA, Nobutaka. Dissolving Microneedles As a Transdermal Delivery System for Adjuvant CpG DNA. 10th Anniversary International Symposium on Nanomedicine. 2016
  6. Yan-Jye Shyong, Feng-Huei Lin, HANAGATA, Nobutaka. Calcium phosphate induce exosome release of human monocyte for exosomal-based drug delivery systems. 10th Anniversary International Symposium on Nanomedicine. 2016
  7. CHINNATHAMBI, Shanmugavel, HANAGATA, Nobutaka. Superparamagnetic CdSe/ZnS Quantum Dot Micelles. 10th Anniversary International Symposium on Nanomedicine. 2016
  8. CHINNATHAMBI, Shanmugavel, HANAGATA, Nobutaka. Binding characteristics of phospholipid coated magnetic CdSe/ZnS quantum dot micelles with human serum albumin. Nano S&T-2016, Singapore. 2016
  9. Yan-Jye Shyong, Feng-Huei Lin, HANAGATA, Nobutaka. Calcium Phosphate Induce Exosome Release of Human Monocyte for Exosomal-based Drug Delivery Systems. Nano S&T-2016, Singapore. 2016
  10. 花方 信孝. 網羅的遺伝子発現解析の生体材料評価への応用. 日本金属学会2016春期(第158回)大会. 2016
  11. HOSHI, Kazuaki, Kaori Tsukakoshi, Koji Sode, Wakako Tsugawa, Kazunori Ikebukuro, HANAGATA, Nobutaka, YAMAZAKI, Tomohiko. DNA structure control immunostimulatory effect of CpG ODN. MANA International Symposium 2016. 2016
  12. CHINNATHAMBI, Shanmugavel, HANAGATA, Nobutaka. Functionalized Near-Infrared Quantum Dots for Biological Applications. Pharmaceutica 2016. 2016
  13. 花方 信孝. 難治性骨疾患の原因遺伝子とその治療戦略. つくば医工連携フォーラム2016. 2016
2015
  1. MANOHARAN, Arun Kumar, CHINNATHAMBI, Shanmugavel, Ramasamy Jayavel, HANAGATA, Nobutaka. The Electrophoretic study to detect the DNA hybridization using monolayer graphene based field effect transistor. 9th International Symposium of Nanomedicine. 2015
  2. CHINNATHAMBI, Shanmugavel, HANAGATA, Nobutaka. Micelle Encapsulated Magnetic Core/Shell Quantum Dots for Biological Applications . 9th International Symposium of Nanomedicine. 2015
  3. HANAGATA, Nobutaka. TLR9-Dependent Type I Interferon Induction by Double-Stranded Phosphodiester CpG ODN complex. 9th International Symposium of Nanomedicine. 2015
  4. 山崎 智彦, ジ チンミン, 花方 信孝, 有賀 克彦. 固相トランスフェクションのためのナノ構造シリカシートの開発. 第37回日本バイオマテリアル学会大会. 2015
  5. 山崎 智彦, 花方 信孝. CpGオリゴヌクレオチドの免疫活性能に対するポリグアノシンの影響. 第67回日本生物工学会大会. 2015
  6. CHEN, Song, HANAGATA, Nobutaka, Akiyoshi Osaka. Silica in nano-fibers, nano-particles, and macrospheres for biomedical applications. 11th IUPAC International Conference on Novel Materials and their. 2015
  7. YAMAZAKI, Tomohiko, SUWARTI, Suwarti, HANAGATA, Nobutaka. Recognition of CpG olygodeoxynucleotides by human Toll-like receptor 9. Toll 2015. 2015
  8. 山崎 智彦, 花方 信孝. ペプチドアプタマーを用いた水酸アパタイトの機能化. 日本セラミックス協会第28回秋季シンポジウム. 2015
  9. CHINNATHAMBI, Shanmugavel, HANAGATA, Nobutaka. CpG ODN Delivery using Silicon Quantum Dots. The 5th Asian Biomaterials Congress. 2015
  10. Min-Hua Chen, TAKEMURA, Taro, MINOWA, Takashi, IKOMA, Toshiyuki, Junzo Tanaka, Feng-Huei Lin, HANAGATA, Nobutaka. Enhancing CpG-DNA delivery for cancer immunotherapy by calcium phosphate nanoparticles. The 5th Asian Biomaterials Congress. 2015
  11. CHEN, Song, HANAGATA, Nobutaka, Wu, Jin Ming, Akiyoshi Osaka. Synthesis of hollow silica flowers and titania nano-flowers for biomedical applications. ICACC 2015. 2015
2014
  1. 花方 信孝. 免疫を制御するDNAナノメディシン. 第3回 NIMS講演会. 2014
  2. CHEN, Song, HANAGATA, Nobutaka, Akiyoshi Osaka. Micro-engineered Silica Nanotube Membranes for Controlled Cell Behaviors. BIOCERAMICS 26. 2014
  3. HANAGATA, Nobutaka. Regulation of Immunostimulatory DNA Drug Action by Nanoparticles. 7th World Congress on Preventive and Regenerative Medicine. 2014
  4. Min-Hua Chen, TAKEMURA, Taro, MINOWA, Takashi, Feng-Huei Lin, HANAGATA, Nobutaka. Hydroxyapatite nanoparticles for enhancing CpG oligodeoxynucleotide delivery in macrophage for cancer immunotherapy. 7th World Congress on Preventive and Regenerative Medicine. 2014
  5. 花方 信孝. 核内タンパク質を標的とした自己免疫抑制. 分子科学研究所研究会「細胞核内反応の分子科学」. 2014
  6. YAMAZAKI, Tomohiko, Yuki Sugiyama, Koji Sode, Wakako Tsugawa, Kazunori Ikebukuro, HANAGATA, Nobutaka. Immunostimulation effect of G-rich CpG oligonucleotide. International Symposium on Smart Biomaterials. 2014
  7. 杉山 雄紀, 早出 広司, 津川 若子, 池袋 一典, 花方 信孝, 山崎 智彦. オリゴグアノシン配列付加によるCpG ODNの免疫活性化能の向上. 分子・物質合成プラットフォーム平成25年度シンポジウム. 2014
  8. YAMAZAKI, Tomohiko, Yuki Sugiyama, Koji Sode, Wakako Tsugawa, Kazunori Ikebukuro, HANAGATA, Nobutaka. G-quadruplex structure extend the immunostimulatory effect of CpG oligodeoxynucleotides. MANA International Symposium 2014. 2014
  9. 花方 信孝. ナノ粒子によるDNAアジュバントの作用制御. 第6回京都SMI産学公連携セミナー. 2014
  10. LI, Xia, Chynui Zhi, HANAGATA, Nobutaka, YAMAGUCHI, Maho, BANDO, Yoshio, GOLBERG, Dmitri. Boron nitride nanotube functionalized with mezoporous silica and targeted antibody for intracellar delivery of chemotherapy drug. ACMM23-ICONN2014. 2014
  11. 杉山 雄紀, 早出 広司, 津川 若子, 池袋 一典, 花方 信孝, 山崎 智彦. オリゴグアノシンを有する免疫活性化オリゴヌクレオチドの開発. つくば医工連携フォーラム2014. 2014
2013
  1. Yusuke SAKAI, Sachiro KAKINOKI, TAKEMURA, Taro, HANAGATA, Nobutaka, Toshia FUJISATO, Tetsuji YAMAOKA. Fibroblast growth factor immobilized polyethylene porous scaffolds via mussel adhesive peptide and heparin for inducing angiogenesis. The 15th International Conference on Biomedical Engineering . 2013
  2. MORITA, Hiromi, HANAGATA, Nobutaka. Calcium Mitigates the Toxicity of Zinc Oxide Nanoparticles to Human Lung Epithelial Cells. 7th International Symposium on Nanomedicine (ISNM2013). 2013
  3. HANAGATA, Nobutaka. Action of Immunostimulatory DNA Drug Can Be Changed by Nanoparticle. 7th International Symposium on Nanomedicine (ISNM2013). 2013
  4. BHEEMA, Deepthi, HANAGATA, Nobutaka. Immunosuppressive DNA Nanomedicine against Autoimmune Disorders. 7th International Symposium on Nanomedicine (ISNM2013). 2013
  5. 山崎 智彦, 花方 信孝. 天然型免疫活性化CpGオリゴデオキシヌクレオチドの開発. 第7回 バイオ関連化学シンポジウム. 2013
  6. 竹田 哲也, 池野 聡一, 市川 大輝, 中野 なおこ, 箕輪 貴司, 花方 信孝, 伊東 史子, 伊東 進. PDZK1IP1によるTGF-βファミリーシグナル伝達経路抑制機構. 第86回日本生化学会大会. 2013
  7. 坂井勇亮, 柿木佐知朗, 竹村 太郎, 花方 信孝, 藤里俊哉, 石原一彦, 山岡哲二. 遺伝子マイクロアレイを用いたポリエチレン多孔質体に対するin vivoでの免疫系細胞の応答解析. 第59回高分子研究発表会. 2013
  8. YAMAZAKI, Tomohiko, ZHANG, Huijie, IKOMA, Toshiyuki, HANAGATA, Nobutaka. Hydroxyapatite-Binding Peptides. STAC-7. 2013
  9. CHEN, Song, HANAGATA, Nobutaka. Chitosan-Silica Nanoparticles for Immunostimulatory DNA Drug Delivery. STAC-7. 2013
  10. 陳 松, 花方 信孝. Synthesis of silica nanotubes as multifunctional materials for biomedical applications. 日本セラミックス協会2013年年会. 2013
  11. HANAGATA, Nobutaka. Regulation of bifurcated cytokine induction by binding mode of CpG DNA onto nanoparticles. 5th Immunotherapeutics & Immunomonitoring Conference . 2013
2012
  1. HANAGATA, Nobutaka. Regulation of Toll-like Receptor 9 mediated Cytokine Profile by Binding Mode of CpG Oligodeoxynucleotides to Nanoparticles. 1st International Conference on Emerging Advanced Nanomaterials . 2012
  2. SUWARTI, Suwarti, YAMAZAKI, Tomohiko, HANAGATA, Nobutaka. Natural CpG ODNs-induced human TLR9 specific immunostimulations . Homeostatic Inflammation Symposium IIEIS 2012. 2012
  3. CHINNATHAMBI, Shanmugavel, Singaravelu Ganesan, HANAGATA, Nobutaka. Preparation and characterization of silicon quantum dots for delivery of nucleic acid drugs. ANM2012(4th International Conference on Advanced Nanomaterials. 2012
  4. HIROMOTO, Sachiko, TOMOZAWA, Masanari, TAKEMURA, Taro, HANAGATA, Nobutaka, MARUYAMA, Norio. Hydroxyapatite Coating prepared by solution treatment on AZ31 Magnesium Alloy. WMRIF - 3rd International Workshop for Young Materials Scientist. 2012
  5. ジュアン フェイ, 花方 信孝. 酸化亜鉛ナノ粒子の毒性に対する肺上皮細胞の応答. 第6回ナノバイオメディカル学会大会. 2012
  6. シナタンビ シャンムガベル, 花方 信孝. 核酸医薬デリバリーのための正電荷を有するシリコン量子ドットの合成と特性. 第6回ナノバイオメディカル学会大会. 2012
  7. 張 慧杰, 山崎 智彦, 支 春義, 花方 信孝. CpG オリゴ核酸送達のための窒化ホウ素ナノ粒子特異的結合ペプチドの同定. 第6回ナノバイオメディカル学会大会. 2012
  8. チェチェトカ スベトラーナ, 山崎 智彦, 花方 信孝. 完全天然型CpG オリゴデオキシヌクレオチドによるインターロイキン-6 誘導特性. 第6回ナノバイオメディカル学会大会. 2012
  9. 陳 松, 花方 信孝. 骨再生のためのシリカナノチューブの合成. 第6回ナノバイオメディカル学会大会. 2012
  10. HIROMOTO, Sachiko, TOMOZAWA, Masanari, TAKEMURA, Taro, HANAGATA, Nobutaka, MARUYAMA, Norio. Hydroxyapatite Coating by Chemical Deposition for a Bioabsorbable Magnesium Alloy. NIMS Conference 2012. 2012
  11. ZHANG, Huijie, YAMAZAKI, Tomohiko, ZHI, Chunyi, HANAGATA, Nobutaka. Peptide with binding specificity for boron nitride nanospheres. 9th World Biomaterials Congress. 2012
  12. ZHANG, Ling, KAIZUKA, Yoshihisa, HANAGATA, Nobutaka. Imaging Fas/FasL Clusters at the Cell-membrane Interface. 9th World Biomaterials Congress. 2012
  13. CHEN, Song, HANAGATA, Nobutaka. Micropatterning of chitosan-silicate hybrids for biomedical applications. the 9th World Biomaterials Congress (WBC). 2012
  14. YAMAZAKI, Tomohiko, MENG, Wenjun, HANAGATA, Nobutaka. New Nuclease-Resistant Immunostimulatory Phosphodiester-based Oligonucleotides for Immune Therapies. 9th World Biomaterials Congress . 2012
  15. YAMAZAKI, Tomohiko, ZHANG, Huijie, IKOMA, Toshiyuki, HANAGATA, Nobutaka. Screening and Characterization of Hydroxyapatite-Specific Binding Peptides. 9th World Biomaterials Congress . 2012
  16. 廣本 祥子, 竹村 太郎, 花方 信孝. 水酸アパタイト被覆AZ31マグネシウム合金表面でのMG-63細胞の短期培養. 日本金属学会2012年春期(第150回)大会. 2012
  17. YAMAZAKI, Tomohiko, ZHANG, Huijie, IKOMA, Toshiyuki, HANAGATA, Nobutaka. Hydroxyapatite-Specific Binding Peptides. The MANA International Symposium. 2012
  18. 山崎 智彦, 張 慧杰, 西田 有紀, 生駒 俊之, 花方 信孝. ハイドロキシアパタイト結合ペプチドの検索. つくば医工連携フォーラム2012. 2012
2011
  1. CHEN, Song, HANAGATA, Nobutaka, Akiyoshi Osaka. Fabrication of silica-based particles and nanotubes for bone generation. The 28th International Japan-Korea Seminar . 2011
  2. YAMAZAKI, Tomohiko, SAKAGUCHI, Akane, Koji SODE, TANIGUCHI, Akiyoshi, HANAGATA, Nobutaka. Engineered transcriptional regulators for intracellular sensing and gene regulation . 日中バイオテクノロジー先端フォーラム2011. 2011
  3. YAMAZAKI, Tomohiko, MENG, Wenjun, HANAGATA, Nobutaka. Novel CpG phosphodiester oligodeoxynucleotides as human toll-like receptor 9 agonists. Infection & Immunity. 2011
  4. SUWARTI, Suwarti, YAMAZAKI, Tomohiko, HANAGATA, Nobutaka. Analysis of CpG ODNS binding of human toll like receptor 9. Infection and Immunity. 2011
  5. OGAWA, Nobuhiro, MitsuhiroOKUDA, HANAGATA, Nobutaka, TAKEGUCHI, Masaki. The structural features of the mineral particles on the surface of the aligned type I collagen fibrils in the fish scale. Gordon research conference on collagen. 2011
  6. ZHANG, Huijie, YAMAZAKI, Tomohiko, ZHI, Chunyi, HANAGATA, Nobutaka. Identification of Boron Nitride Nanospheres Binding Peptides. The Symposium on Micro/Nano Aspects of Biomaterials. 2011
  7. CHINNATHAMBI, Shanmugavel, NAGARAJAN, Venkata Krishnan, ARIGA, Katsuhiko, HANAGATA, Nobutaka. Water soluble silicon quantum dots as fluorescent probes for bio-applications. The Symposium on Micro/Nano Aspects of Biomaterials. 2011
  8. ZHANG, Ling, KAIZUKA, Yoshihisa, HANAGATA, Nobutaka. Imaging Study of Proteins Interaction Following the Contact of Living Cell to Artificial Membrane. The Symposium on Micro/Nano Aspects of Biomaterials. 2011
  9. MENG, Wenjun, YAMAZAKI, Tomohiko, HANAGATA, Nobutaka. Novel Phosphodiester CpG Oligodeoxynucleotides with High Stimulatory Effects on Human Toll-like Receptor 9. The Symposium on Micro/Nano Aspects of Biomaterials . 2011
  10. SUWARTI, Suwarti, YAMAZAKI, Tomohiko, HANAGATA, Nobutaka. C-terminal ligand binding analysis of human Toll-like receptor 9. The Symposium on Micro.Nano Aspects of Biomaterials. 2011
  11. ZHU, Yufang, HANAGATA, Nobutaka. Design of Mesoporous Silica/CpG ODN Complexes to Enhance Delivery Efficiency. ICMAT 2011. 2011
  12. Osaka Akiyoshi, CHEN, Song, HANAGATA, Nobutaka, Yuki SHIROSAKI, Satoshi HAYAKAWA. Sol-Gel preparation of silica-based nano-particles and fibers for biomedical applications. the 3rd IC4N 2011. 2011
  13. YAMAZAKI, Tomohiko, HANAGATA, Nobutaka. Identification of Hydroxyapatite-Binding Peptides. STAC5-AMDI2. 2011
  14. YAMAZAKI, Tomohiko, MENG, Wenjun, ZHI, Chunyi, ZHU, Yufang, HANAGATA, Nobutaka. Novel CpG oligodeoxynucleotide and its delivery system. Bio Nanotech 2011. 2011
  15. ZHU, Yufang, HANAGATA, Nobutaka. Folate-Conjugated Fe3O4@SiO2 Hollow Mesoporous Spheres as Potential Carriers for Targeted Drug Delivery. Second International Conference on Multifunctional, Hybrid and N. 2011
  16. ZHANG, Ling, KAIZUKA, Yoshihisa, HANAGATA, Nobutaka. Imaging Studies of Membrane Microdomain in FasL-mediated Apoptosis. 融合生命科学若手シンポジウム. 2011
  17. ZHUANG, Fei, YAMAZAKI, Tomohiko, HANAGATA, Nobutaka. Molecular mechanism on toxicity of CuO nanoparticles. 融合生命科学若手シンポジウム. 2011
  18. ZHANG, Huijie, YAMAZAKI, Tomohiko, HANAGATA, Nobutaka. Screening of Peptides Selectively Binding to Boron Nitride Nanoparticles. 融合生命科学若手シンポジウム. 2011
  19. ZHU, Yufang, HANAGATA, Nobutaka. Hollow Mesoporous Silica Spheres for Drug Delivery. MANA International Symposium 2011 . 2011
  20. MENG, Wenjun, YAMAZAKI, Tomohiko, HANAGATA, Nobutaka. Screening of CpG ODN as TLR9 agonist for pollinosis therapy. 融合生命科学若手シンポジウム. 2011
  21. 徐明生, FUJITA, Daisuke, SAGISAKA, Keisuke, WATANABE, Eiichiro, HANAGATA, Nobutaka. Production of extended single-layer graphene. MANA International Symposium 2011. 2011
  22. SUWARTI, Suwarti, YAMAZAKI, Tomohiko, HANAGATA, Nobutaka. Ligand-binding and signaling of Toll-like receptor 9. 融合生命科学若手シンポジウム. 2011
  23. YAMAZAKI, Tomohiko, HANAGATA, Nobutaka. Enhancement of the therapeutic efficiency of a human toll-like receptor 9 agonist via bio- and nano- technology. International Workshop on Biomedical Sciences and Technologies. 2011
  24. 支 春義, 孟 文君, 山崎 智彦, 板東 義雄, ゴルバーグ デミトリ, 花方 信孝. BN nanospheres as CpG ODN carrier for activation of toll-like receptor 9. Symposium of Nano Biomedical Society. 2011
  25. 孟 文君, 山崎 智彦, 花方 信孝. Construction of nuclease-resistant phosphodiester CpG oligonucleotides for pollinosis therapy. ナノ・バイオメディシンシンポジウム (第4回ナノ・バイオメディカル. 2011
  26. ズー ユーファン, 花方 信孝. Fe3O4@SiO2 Hollow Mesoporous Spheres as Potential Carriers for Anticancer Drug Delivery. ナノ・バイオメディシン シンポジウム. 2011
  27. 張 玲, 貝塚 芳久, 花方 信孝. Molecular Organizations at the Live Cell-biomembrane Interface. ナノ・バイオメディシンシンポジウム (第4回ナノ・バイオメディカル. 2011
  28. CHEN, Song, Toshiyuki Ikoma, LI, Jie, MORITA, Hiromi, Akiyoshi Osaka, TAKEGUCHI, Masaki, HANAGATA, Nobutaka. Collagen-templated sol-gel preparation of ultra-fine silica nanotube films and osteoblastic cell proliferation. 35th International Conference & Exposition on Advanced Ceramics . 2011
2010
  1. 孟 文君, 山崎 智彦, 花方 信孝. Development of novel CpG oligodeoxynucleotides for Toll-like receptor 9 activation. BMB2010(第33回日本分子生物学会年会・第83回日本生化学会大会 合. 2010
  2. ズー ユーファン, 花方 信孝. Fe3O4@SiO2 Hollow Mesoporous Spheres as Carriers for Drug Delivery. 第32回日本バイオマテリアル学会. 2010
  3. 陳 松, 生駒俊之, 尾坂 明義, 花方 信孝. Development of novel silica nanotube scaffolds using collagen fibril hydrogels as novel templates. 第32回日本バイオマテリアル学会大会. 2010
  4. 江橋具, 柿木佐知朗, 竹村 太郎, 箕輪 貴司, 花方 信孝, 小林 尚俊, 由井伸彦, 石原一彦, 山岡哲二. 皮下に埋入したバイオマテリアル界面に対する生体応答の遺伝子網羅解析. 第32回日本バイオマテリアル学会. 2010
  5. CHEN, Song, Toshiyuki Ikoma, TAKEGUCHI, Masaki, HANAGATA, Nobutaka. In vitro bioactivity of Ca-containing silica hollow fiber scaffolds. the 10th Asian BioCeramics Symposium 2010 (ABC 2010) . 2010
  6. ZHU, Yufang, HANAGATA, Nobutaka. Rattle-type Fe3O4@SiO2 Hollow Mesoporous Spheres as Potential Carriers for Anticancer Drug delivery. The 10th Asian BioCeramics Symposiun 2010. 2010
  7. 右田 聖, 津谷 大樹, 杉本 喜正, 生駒俊之, 花方 信孝, 山崎 智彦. マイクロ流路を利用した細胞のサイズ分離による細胞周期同調. 第62回日本生物工学会大会. 2010
  8. ZHU, Yufang, HANAGATA, Nobutaka. Hollow Mesoporous Silica Spheres as Carriers for Drug Delivery. IDDST 2010. 2010
  9. ZHU, Yufang, HANAGATA, Nobutaka, KOBAYASHI, Hisatoshi. Modified Hollow Mesoporous Spheres as Carriers for Targeted Drug Delivery. 11th IUMRS International Conference in Asia. 2010
  10. 大川美佳, 陳 松, 小川 展弘, 花方 信孝, 多賀谷 基博, 生駒 俊之, 浦和 寛, 都木靖彰. ティラピアI型コラーゲンの熱安定性と線維化能. 平成22年度日本水産学会秋季大会. 2010
  11. 徐明生, FUJITA, Daisuke, HANAGATA, Nobutaka. Scanning Auger Electron Spectroscopy of Graphene layers. 2010年秋季 第71回 応用物理学会学術講演会. 2010
  12. CHEN, Song, IKOMA, Toshiyuki, HANAGATA, Nobutaka. Rheological Properties of Magnetically Aligned Collagen Fibril Hydrogels. 23rd European Conference on Biomaterials (ESB2010). 2010
  13. 徐明生, FUJITA, Daisuke, HANAGATA, Nobutaka. Electron-beam irradiation effect on graphene layers. 18th International Vacuum Congress (IVC-18). 2010
  14. 徐明生, FUJITA, Daisuke, HANAGATA, Nobutaka. Scanning Auger electron spectroscopy: A rational method for characterization of graphene layers. Recent Advances in Graphene and Related Materials. 2010
  15. Tatshuyuki Takadate, Toru Onogawa, Kiyonaga fujii, Shinpei Maeda, TAKEMURA, Taro, Sayaka Mikami, Seiko Yamada, Tetsuya Fukuda, Yasuhiko Bando, Fumihiko Usui, Shinichi Egawa, MINOWA, Takashi, HANAGATA, Nobutaka, Toshihide Nishimura, Toshiki Rikiyama, Tomo Katayori, Michiaki Umino. Discovery of Prognostic Factor using Proteomic Analysis with Formalin-Fixed Paraffin-. 第14回国際膵臓学会・第41回日本膵臓学会大会. 2010
  16. 塚本 卓, リ コウラン, 花方 信孝, 出村 誠. Expression, purification and characterization of osteoblastspecific membrane protein Ifitm5 in detergent solubilized system. Annual Meetings. 10th PSSJ annual meeting. 2010
  17. 徐明生, FUJITA, Daisuke, HANAGATA, Nobutaka. Scanning Auger Electron Spectroscopy: a New and Universal Technique for Identifying Graphene. Internation Conference on Modern Materials & Technilogies. 2010
  18. 前田晋平, 小野川徹, 高舘達之, 森川孝則, 竹村 太郎, 三上紗弥香, 山田誠子, 福田哲也, 板東泰彦, 碓井史彦, 箕輪 貴司, 花方 信孝, 西村俊秀, 力山敏樹, 片寄 友, 江川新一, 海野倫明. FFPE組織を用いた網羅的プロテオーム解析による胆道癌新規バイオマーカーの探索. 第22回日本肝胆膵外科学会・学術集会. 2010
  19. 高舘達之, 小野川徹, 前田晋平, 森川孝則, 竹村 太郎, 元井冬彦, 三上紗弥香, 山田誠子, 福田哲也, 板東泰彦, 碓井史彦, 箕輪 貴司, 花方 信孝, 西村俊秀, 力山敏樹, 片寄 友, 江川新一, 海野倫明. ホルマリン固定パラフィン包埋組織を用いた臨床プロテオミクスによる膵癌新規バイ. 第22回日本肝胆膵外科学会・学術集会. 2010
  20. 小野川徹, 前田晋平, 高舘達之, 竹村 太郎, 三上紗弥香, 福田哲也, 山田誠子, 板東泰彦, 碓井史彦, 箕輪 貴司, 花方 信孝, 西村俊秀, 森川孝則, 元井冬彦, 力山敏樹, 片寄 友, 江川新一, 海野倫明. 病院保管のホルマリン固定化永久組織からプロテオーム解析はどこまでできるか?. 第22回日本肝胆膵外科学会・学術集会. 2010
  21. 徐明生, FUJITA, Daisuke, HANAGATA, Nobutaka. The Effect of Physicochemical Properties of Nano-oxides on Cytotoxicity. First World Conference On Nanomedicine And Drug Delivery. 2010
  22. 花方 信孝. DNA Microarrayを用いた材料の表面化学的・物理的特性に対する細胞応答反応の解明. 日本金属学会2010年春期(第146回)大会講演. 2010
  23. TAGAYA, Motohiro, IKOMA Toshiyuki, HANAGATA, Nobutaka, YOSHIOKA Tomohiko, TANAKA Junzo. Competitive adsorption of fibronectin and albumin on hydroxyapatite nanocrystals analyzed in situ by a quartz crystal microbalance with dissipation technique. 239th American Chemical Society National Meeting & Exposition. 2010
  24. 奥田 充宏, 竹口 雅樹, 小川 展弘, 橋本 綾子, 多賀谷 基博, 陳 松, 花方 信孝, 生駒 俊之. 魚鱗中のリン酸カルシウム分布. セラミックス協会 2010年 年会 「セラミックスに関する顕微鏡写真展. 2010
  25. 花方 信孝. 遺伝子発現解析のバイオマテリアルへの応用. 次世代バイオマテリアルを考える会. 2010
  26. 徐明生, FUJITA, Daisuke, HANAGATA, Nobutaka. The Effect of Physiochemical Properties of Nano-Oxides on Cytotoxicity. MANA International Symposium 2010. 2010
  27. 有坂 智帆, 多賀谷 基博, 生駒 俊之, 花方 信孝. SPR法を用いた水酸アパタイトナノ結晶表面へのフィブリノーゲンの結合挙動の計測. 第48回セラミックス基礎科学討論会. 2010
2009
  1. 徐 麗明, 箕輪 貴司, 花方 信孝, 森田 浩美. 骨芽細胞特異的膜タンパク質IFITM5の機能解析:プロモーター領域の解析. 第32回日本分子生物学会年会. 2009
  2. 李 潔, 前田 めぐみ, 箕輪 貴司, 花方 信孝. 骨芽細胞特異的膜タンパク質IFITM5の機能解析:ノックアウトマウスの解析. 第32回日本分子生物学会年会. 2009
  3. リ コウラン, 梶原 祥子, 箕輪 貴司, 花方 信孝. 骨芽細胞特異的膜タンパク質IFITM5の機能解析:相互作用タンパク質ネットワークの解明. 第32回分子生物学会年会. 2009
  4. 徐 明生, 藤田 大介, 花方 信孝. Characterization of Nanomaterials for Risk Assessment. 平成21年度NIMSナノ計測センター研究成果発表会 - 公開セミナー. 2009
  5. 徐明生, FUJITA, Daisuke, GAOJian-Hua, WATANABE, Eiichiro, HANAGATA, Nobutaka. Large-scale, uniform and transferrable graphene films synthesized by chemical vapor deposition. 2009 International Microprocesses and Nanotechnology Conference. 2009
  6. 江橋 具, 竹村 太郎, 箕輪 貴司, 花方 信孝, 小林 尚俊, 山岡 哲二. スキャフォールド材料に対する生体反応の遺伝子網羅的解析. 第31回日本バイオマテリアル学会大会. 2009
  7. 塚本卓, リ コウラン, 神谷昌克, 花方 信孝, 出村誠. Structureal study of Ifitm5, a human double transmembrane protein; optimization for NMR sample preparation. 第47回日本生物物理学会年会. 2009
  8. TAGAYA, Motohiro, IKOMA, Toshiyuki, TAKEMURA, Taro, OKUDA, Mitsuhiro, Tomohiko Yoshioka, HANAGATA, Nobutaka, Tanaka Junzo. Initial adhesion behavior of fibroblasts onto hydroxyapatite nano-crystals. 22nd International Symposium on Ceramics in Medicine. 2009
  9. IKOMA, Toshiyuki, TAGAYA, Motohiro, YAMAZAKI, Tomohiko, TAKEMURA, Taro, HANAGATA, Nobutaka. Hepatocyte adhesion behavior on modified hydroxyapatite nanocrystals with quartz crystal microbalance. 22nd International Symposium on Ceramics in Medicine. 2009
  10. TONEGAWA, Toru, IKOMA, Toshiyuki, SUETSUGU, Yasushi, IGAWANaoki, MATSUSHITA, Yoshitaka, YOSHIOKATomohiko, HANAGATA, Nobutaka, TANAKAJunzo. Crystal structure of high purity type A carbonate apatite. BIOCERAMICS22. 2009
  11. ZHU, Yufang, IKOMA, Toshiyuki, HANAGATA, Nobutaka. Rattle-Type Fe3O4@SiO2 Hollow Mesoporous Spheres as Carriers for Drug Delivery. BIT’s 7th Annual Congress of International Drug Discovery Scien. 2009
  12. HANAGATA, Nobutaka. GENE EXPRESSION PROFILE OF OSTEOBLAST-LIKE CELLS ON CALCIUM PHOSPHATE BIOMATERIALS. International Conference on Quality Control of Biomaterials and . 2009
  13. 大家渓, 竹村 太郎, 花方 信孝, 森山義之, 野田和彦, 堤祐介, 土居壽, 野村直之, 塙隆夫. チタン、ジルコニウム、金における骨芽細胞様細胞骨分化特性の網羅的遺伝子発現解析. 日本金属学会2009年秋期講演大会. 2009
  14. 徐 明生, 藤田 大介, 高 鴻, 梶原 祥子, リ コウラン, 箕輪 貴司, 花方 信孝. Comparative Evaluation of Cytotoxicity of Nano-Oxides. 秋季第70回応用物理学会学術講演会. 2009
  15. ZHU, Yufang, IKOMA, Toshiyuki, HANAGATA, Nobutaka. Efficient Route to Rattle-type Fe3O4@SiO2 Hollow Mesoporous Spheres and Their Intracellular Localization and Cytotoxicity. International Conference on Nanoscience & Technology, China 2009. 2009
  16. 徐明生, FUJITA, Daisuke, GAO, Hong, 梶原祥子, LI, Xianglan, MINOWA, Takashi, HANAGATA, Nobutaka. Comparative Evaluation of Nano-Oxides Impact on Cellular Response. ChinaNANO2009 -International Conference on Nanosci. and Technol.. 2009
  17. 徐明生, FUJITA, Daisuke, GAO, Hong, 梶原祥子, LI, Xianglan, MINOWA, Takashi, HANAGATA, Nobutaka. Comparative Evaluation of Nano-Oxides Impact on Cellular Response. ChinaNANO 2009. 2009
  18. 小野川徹, 前田晋平, 岡上能斗竜, 高舘達之, 石田和之, 前田 めぐみ, 竹村 太郎, 三上紗弥香, 遠藤洋子, 山田誠子, 西山隆太郎, 箕輪 貴司, 花方 信孝, 板東泰彦, 碓井史彦, 西村俊秀, 力山敏樹, 片寄友, 江川新一, 海野倫明. 胆道癌ホルマリン固定パラフィン包埋組織切片からのディスカバリープロテオミクス. 日本ヒトプロテオーム機構(JHUPO)第7回大会. 2009
  19. 徐明生, FUJITA, Daisuke, HANAGATA, Nobutaka. Characterization of nanomaterials for nanorisk assessment. NIMS week 2009. 2009
  20. 花方 信孝. ナノテクノロジー・ネットワークにおける取り組みと産学官研究者支援によるイノベーション創出. 第2回東北大学医学系NM-GCOE拠点シンポジウム. 2009
  21. 多賀谷基博, 生駒俊之, 奥田充宏, TAKEMURA, Taro, 吉岡朋彦, HANAGATA, Nobutaka, 田中順三. Monitoring of Adsorption of Multiple Proteins onto Hydroxyapatite Nanosensor by Quartz Crystal Microbalance with Dissipation Technique. The Third International Conference on the Science and Technology. 2009
  22. HANAGATA, Nobutaka. Gene expression profile of osteoblasts cultured on various surface structures . 2009 UW CNT Conference on Nanotechnology & UW/NIMS MOLAT Forum. 2009
  23. IKOMA, Toshiyuki, TAGAYA, Motohiro, YAMAZAKI, Tomohiko, HANAGATA, Nobutaka. In situ analyzes of interfacial interaction between cells and biomaterials by using quartz crystal microbalance with dissipation technique. 8th International Symposium on Frontiers in Biomedical Polymers. 2009
  24. 小野川徹, 前田晋平, 岡上能斗竜, 森川孝則, 高舘達之, 石田和之, 前田 めぐみ, 竹村 太郎, 三上紗弥香, 遠藤洋子, 山田誠子, 西山隆太郎, 箕輪 貴司, 花方 信孝, 板東泰彦, 碓井史彦, 西村俊秀, 力山敏樹, 片寄友, 江川新一, 海野倫明. 胆道癌ホルマリン固定パラフィン包埋(FFPE)組織からのディスカバリープロテオミクス. 第5回 日本臨床プロテオーム研究会2009. 2009
  25. 徐 明生, 藤田 大介, 梶原 祥子, リ コウラン, 箕輪 貴司, 花方 信孝. Nanoparticle effect on NIH3T3 cell viability. 2009年(平成21年)春季第56回応用物理学関係連合講演会. 2009
  26. 徐明生, FUJITA, Daisuke, 梶原祥子, LI, Xianglan, MINOWA, Takashi, HANAGATA, Nobutaka. ZnO Nanostructures-Mediated Cell viability. MANA International Symposium 2009. 2009
2008
  1. 森田 浩美, 竹村 太郎, リ コウラン, 箕輪 貴司, 花方 信孝. 骨芽細胞特異的な新奇遺伝子Ifitm5. 第31回日本分子生物学会年会. 2008
  2. リ コウラン, 箕輪 貴司, 花方 信孝. 骨芽細胞特異的膜タンパク質IFITM5と相互作用するタンパク質の同定. BMB2008第31回日本分子生物学会年会. 2008
  3. 高森 靖, 箕輪 貴司, SEGAWA Yushi, TAKAO Tukasa, SUZUKI Keiko, SUZUKI Keiko, ASAI Yoshiaki, NOGAKI Kaneo, 花方 信孝. 臍帯血由来CD133陽性細胞におけるES関連遺伝子の発現と臍帯由来細胞を用いた幹細胞性の維持. 第38回日本免疫学会総会. 2008
  4. 張 伶俐, 花方 信孝, 前田 めぐみ, 箕輪 貴司, Hongsong Fan, Xingdong Zhang. Osteoblast induction by porous calcium phosphate ceramics implanted into rat muscle. 日本バイオマテリアル学会シンポジウム2008. 2008
  5. 山吉誠也, 山下康子, 花方 信孝, 箕輪 貴司, 竹村 太郎, 清水博之, 小池智. エンテロウイルス71の感染性決定分子の同定. 第56回 日本ウイルス学会学術集会. 2008
  6. TAGAYA, Motohiro, IKOMA, Toshiyuki, TAKEMURA, Taro, OKUDA, Mitsuhiro, HANAGATA, Nobutaka. Adsorption of Proteins Derived from Fetal Bovine Serum onto Hydroxyapatite Nanocrystals with Quartz Crystal Microbalance Techniq. 21st International Symposium of Ceramics in Medicine. 2008
  7. 吉江幸子, 池畑政輝, 早川敏雄, 廣田 憲之, 竹村 太郎, 箕輪 貴司, 花方 信孝. 活性酸素除去機能を欠損する大腸菌による強磁場13 Tの変異原性評価. 日本磁気科学会第3回年次大会. 2008
  8. 利根川 亨, 生駒 俊之, 吉岡 朋彦, 篠崎 和夫, 花方 信孝, 田中 順三. 結晶子サイズの異なる水酸アパタイトのタンパク質吸着能評価. 日本セラミックス協会 第21回秋季シンポジウム(2008年). 2008
  9. 多賀谷基博, 生駒俊之, 竹村太郎, 奥田充宏, 花方信孝. QCM-Dを用いた水酸アパタイトナノ結晶表面へ吸着したタンパク質の除去の解析. 第21回セラミックス協会秋季シンポジウム. 2008
  10. 吉江幸子, 池畑政輝, 早川敏雄, 廣田 憲之, 竹村 太郎, 箕輪 貴司, 花方 信孝. 活性酸素除去機能を欠損する大腸菌による強磁場13Tの変異原性評価. 第32回日本磁気学会学術講演会. 2008
  11. IKOMA, Toshiyuki, HANAGATA, Nobutaka, tanaka jyunzo. Protein Nanofilms Patterned on Hydroxyapatite. The 8th World Biomaterials Congress. 2008
  12. TONEGAWA, Toru, IKOMA, Toshiyuki, YOSHIOKA Tomohiko, SHINOZAKI Kazuo, HANAGATA, Nobutaka, TANAKA, Junzo. Pharmacological Protein Adsorption on Nano Crystalline Zinc containing Hydroxyapatite . 8th World Biomaterials Congress 2008. 2008
2007
  1. TAKEMURA, Taro, IKOMA, Toshiyuki, HANAGATA, Nobutaka. Stimulation of Osteoblast Maturation by Acid Treated Hydroxyapatite Surface. 1st Asian Biomaterials Congress. 2007
  2. 利根川 亨, 生駒 俊之, 吉岡 朋彦, 篠崎 和夫, 花方 信孝, 田中 順三. 亜鉛含有量によるアパタイトの蛋白質吸着挙動. 第11回生体関連セラミックス討論会. 2007
  3. 高森靖, 鈴木恵子, 浅井芳明, 野垣兼朗, 竹村 太郎, 花方 信孝. Stem Cell Gene Expression on Cord Blood Cells with the Lapse of Time after Harvest. 第37回日本免疫学会総会. 2007
  4. Sachiko Yoshie, Masateru Ikehata, HIROTA, Noriyuki, TAKEMURA, Taro, MINOWA, Takashi, HANAGATA, Nobutaka, Toshio Hayakawa. Effects of Static Magnetic Fields on Escherichia coli deficient in superoxide dismutase. The International Conference on Magneto-Science ICMS2007. 2007
  5. TONEGAWA, Toru, IKOMA, Toshiyuki, YOSHIOKA Tomohiko, SHINOZAKI Kazuo, HANAGATA, Nobutaka, TANAKA, Junzo. Study on the Pharmacological Protein Adsorption on Nano Crystalline Zinc containing Hydroxyapatite. International Symposium on Sustainable Energy & Materials. 2007
  6. IKOMA, Toshiyuki, Tomohiko Yoshioka, Satoshi Nakamura, Tetuya Abe, HANAGATA, Nobutaka, Masataka Sakane, Naoyuki Ochiai, Junzo Tanaka. Rigid Hydroxyapatite Alginate Beads for Sustained Release of Paclitaxel. Bioceramics 20. 2007
  7. Yoshioka Tomohiko, IKOMA, Toshiyuki, TONEGAWA, Toru, HANAGATA, Nobutaka, Chakarov D, Kasemo B, Tanaka Junzo. Protein Adsorption on Hydroxyapatite Nano-crystals with Quartz Crystal Microbalance Technique. Bioceramic 20. 2007
  8. 利根川 亨, 生駒 俊之, 吉岡 朋彦, 花方 信孝, 田中 順三. 合成温度による金属イオン含有水酸アパタイトのタンパク質吸着、放出特性への影響. 第29回日本バイオマテリアル学会大会. 2007
  9. REITER, Michal, HANAGATA, Nobutaka, Plasek Jaromir. Structural changes of yeast cell wall cultured in different glucose concentration. European Biophysics Congress. 2007
  10. REITER, Michal, IKOMA, Toshiyuki, HANAGATA, Nobutaka, Roguska Agata. FORMATION OF TYPE I COLLAGEN FIBRILS FROM PORCINE DERMIS AND FISH SCALE OBSERVED BY AFM. Nanostructured Polymers and Polymer Nanocomposites. 2007
  11. 横山 敬郎, 竹村 太郎, 花方 信孝, 小林 尚俊. 高分子-タンパク混紡型ナノファイバーの細胞接着性と構造解析. 第56回 高分子学会年次大会. 2007
2006
  1. 深山真史, 花方 信孝, 多田雄一. マングローブ植物のEST解析とcDNAマイクロアレイによる耐塩性遺伝子の探索. 日本分子生物学会2006フォーラム. 2006
  2. KIKUCHI, Masanori, SUETSUGU, Yasushi, IKOMA, Toshiyuki, TAGUCHI, Tetsushi, KOBAYASHI, Hisatoshi, CHEN, Guoping, MARUYAMA, Norio, YAMAMOTO, Akiko, HIROMOTO, Sachiko, SHIRAI, Yoko, UCHIDA, Yoshiyuki, SAKATA, Toshiya, HANAGATA, Nobutaka, MIYAHARA, Yuji, OKUDA, Junko, TANIGUCHI, Akiyoshi, TATEISHI, Tetsuya. Toward New Medical Treatment for Extremely Aged Society. 2006 POWDER METALLURGY World Congress and Exhibition (PM2006) . 2006
  3. 花方 信孝. 骨芽様細胞の網羅的遺伝子発現解析によるリン酸カルシウムセラミックスの評価. 日本セラミック協会第19回秋季シンポジウム. 2006
  4. 紋川 亮, 生駒 俊之, 花方 信孝, 田中 順三. ナノサーチ顕微鏡による細胞外マトリックスの観察. 第53回応用物理学関係連合講演会講演. 2006
2005
  1. HANAGATA, Nobutaka. Evaluation of biomaterials by DNA microarray techniques. Seminar on Futuristic Trends in Biotechnology. 2005
  2. 花方 信孝. DNAマイクロアレイによる生体材料の評価. アパタイトゲノミクス研究会. 2005

特許 TSV

登録特許
  1. 特許第6425340号 コロイド溶液、シリカナノシート網目構造体被覆基材、遺伝子トランスフェクション用基材及びコロイド溶液の製造方法 (2018)
  2. 特許第5930146号 免疫刺激オリゴヌクレオチドおよび前記免疫刺激オリゴヌクレオチドを含む治療剤 (2016)
  3. 特許第5586001号 ナノリボン及びその製造方法、ナノリボンを用いたFET及びその製造方法、ナノリボンを用いた塩基配列決定方法およびその装置 (2014)
  4. 特許第5201507号 生体適合性材料の表面浄化方法とそれに用いる洗浄装置 (2013)
公開特許出願
  1. 特開2010099049号 実験動物とそれを用いた骨疾患改善能の評価方法 (2010)
外国特許
  1. No. WO2017007027A1 IMMUNE-STIMULATING OLIGONUCLEOTIDE COMPLEX (2017)

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