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Research papers TSV
2022
- Anh Thi Tram Tu, Kazuaki Hoshi, Tomohiko Yamazaki. Influence of loop permutation on immunostimulatory activities of CpG oligodeoxynucleotides forming monomeric guanine-quadruplex structures. Biomedical Research and Therapy. 9 [11] (2022) 5410-5417 10.15419/bmrat.v9i11.780
- Dandan Zhao, Anh Thi Tram Tu, Miwako Shobo, Nguyen Bui Thao Le, Chiaki Yoshikawa, Kazuhisa Sugai, Yoji Hakamata, Tomohiko Yamazaki. Non-Modified CpG Oligodeoxynucleotide Forming Guanine-Quadruplex Structure Complexes with ε-Poly-L-Lysine Induce Antibody Production as Vaccine Adjuvants. Biomolecules. 12 [12] (2022) 1868 10.3390/biom12121868
- Anh Thi Tram Tu, Kazuaki Hoshi, Yue Ma, Taiji Oyama, Satoko Suzuki, Kaori Tsukakoshi, Kazuo Nagasawa, Kazunori Ikebukuro, Tomohiko Yamazaki. Effects of G-Quadruplex Ligands on the Topology, Stability, and Immunostimulatory Properties of G-Quadruplex-Based CpG Oligodeoxynucleotides. ACS Chemical Biology. 17 [7] (2022) 1703-1713 10.1021/acschembio.1c00904
- Anh Thi Tram Tu, Kazuaki Hoshi, Miwako Shobo, Tomohiko Yamazaki. G-quadruplex-based CpG oligodeoxynucleotide/DOTAP complex strongly stimulates immunity in CpG motif-specific and loop-length-dependent manners. Nanomedicine: Nanotechnology, Biology and Medicine. 40 (2022) 102508 10.1016/j.nano.2021.102508
2021
- Fika Ayu Safitri, Anh Thi Tram Tu, Kazuaki Hoshi, Miwako Shobo, Dandan Zhao, Arief Budi Witarto, Sony Heru Sumarsono, Ernawati Arifin Giri-Rachman, Kaori Tsukakoshi, Kazunori Ikebukuro, Tomohiko Yamazaki. Enhancement of the Immunostimulatory Effect of Phosphodiester CpG Oligodeoxynucleotides by an Antiparallel Guanine-Quadruplex Structural Scaffold. Biomolecules. 11 [11] (2021) 1617 10.3390/biom11111617
2020
- Anh Thi Tram Tu, Kazuaki Hoshi, Kazunori Ikebukuro, Nobutaka Hanagata, Tomohiko Yamazaki. Monomeric G-Quadruplex-Based CpG Oligodeoxynucleotides as Potent Toll-Like Receptor 9 Agonists. Biomacromolecules. 21 [9] (2020) 3644-3657 10.1021/acs.biomac.0c00679
Books TSV
Proceedings TSV
Presentations TSV
2022
- 山崎 智彦, サフィトリ フィーカ アユ, ツ チ トラム アン, レ ボイ タオ グエン, パタク ソウミトラ, 塚越かおり, 池袋一典. 逆平行グアニン四重鎖構造をスキャフォールドとして用いた未修飾CpGオリゴデオキシヌクレオチドの免疫活性化効果. 第16回バイオ関連化学シンポジウム. 2022
- ZHAO, Dandan, TU, Thi Tram Anh, YOSHIKAWA, Chiaki, YAMAZAKI, Tomohiko. ε-Poly-L-Lysine / Guanine-Quadruplexes CpG Oligodeoxynucleotide Complexes for Vaccine Adjuvant Applications. つくば医工連携フォーラム2022, つくばバイオマテリアル医工学研究会. 2022
2021
- 塚越かおり, 鈴木仁子, 大山泰史, 佐藤星, ツ チ トラム アン, 堀口靖夫, 永森浩司, 山崎 智彦, 池袋一典. Development of functional oligonucleotides forming G-quadruplex structure by using topological structure evaluation based on CD spectrum analysis combined with principal component analysis. 日本核酸医薬学会第6回年会. 2021
- 山崎 智彦, ツ チ トラム アン, 星 和明, サフィトリ フィーカ アユ, 塚越かおり, 池袋一典. Development of Guanine-Quadruplex Structure based CpG Oligodeoxynucleotide. 日本核酸医薬学会第6回年会. 2021
2020
- 山崎 智彦, 星 和明, ツ チ トラム アン, 吉川 千晶, 菅井 和久, 袴田 陽二. 水溶性ヘムポリマーのアジュバント効果. 第15回ナノ・バイオメディカル学会年会. 2020
- TU, Thi Tram Anh, HOSHI, Kazuaki, 池袋 一典, YAMAZAKI, Tomohiko. Forming Monomeric Guanine-Quadruplex Structure for enhancing CpG oligodeoxynucleotides-mediated immunostimulatory properties. 第15回ナノ・バイオメディカル学会年会. 2020
- TU, Thi Tram Anh, HOSHI, Kazuaki, 池袋 一典, HANAGATA, Nobutaka, YAMAZAKI, Tomohiko. Enhanced Immunostimulatory Activity of CpG Oligodeoxynucleotides by Forming Monomeric Guanine-Quadruplex Structure. 16th Annual Meeting of the Oligonucleotide Therapeutics Society. 2020
- TU, Thi Tram Anh, HOSHI, Kazuaki, 池袋 一典, YAMAZAKI, Tomohiko. Tuning of the immunostimulatory effect of G-quadruplex based CpG Oligodeoxynucleotides. MANA International Symposium 2020 jointly with ICYS. 2020
- 山崎 智彦, 星 和明, ツ チ トラム アン, 吉川 千晶, 津川 若子, 池袋 一典, 早出 広司. 水溶性ヘム含有ポリマーの合成と免疫活性化能の検討. 第13回次世代アジュバント研究会. 2020
2019
- ツ チ トラム アン, 山崎 智彦, 吉川 千晶, 星 和明, 池袋 一典, 早出 広司, 津川 若子, 免疫活性化能を有するヘミン含有共重合体の開発. 第41回日本バイオマテリアル学会大会. 2019
- TU, Thi Tram Anh, HOSHI, Kazuaki, 池袋 一典, YAMAZAKI, Tomohiko. Immunostimulatory properties of CpG ODNs forming G-quadruplex structure. 46th International Symposium on Nucleic Acids Chemistry. 2019
- HOSHI, Kazuaki, TU, Thi Tram Anh, 塚越 かおり, 津川 若子, 早出 広司, 池袋 一典, YAMAZAKI, Tomohiko. Improvement of the immunostimulatory effects of CpG ODNs by forming G-quadruplex structure. 46th International Symposium on Nucleic Acids Chemistry. 2019
- YAMAZAKI, Tomohiko, HOSHI, Kazuaki, TU, Thi Tram Anh, 塚越かおり, 津川若子, 早出広司, 池袋一典. G-quadruplex structure improves the immunostimulatory effects of CpG oligonucleotides. 第71回日本生物工学会大会. 2019
Misc TSV
2021
- 山崎 智彦, TU Ti Tram Anh. グアニン四重鎖構造形成オリゴ核酸の構造評価と核酸医薬品への応用. Ｄｒｕｇ Ｄｅｌｉｖｅｒｙ Ｓｙｓｔｅｍ. 36 [5] (2021) 360-368 10.2745/dds.36.360