There is a growing demand for memory devices that can meet emerging societal needs, such as wearable and disposable memory technologies. Organic nonvolatile memories based on flexible organic materials are promising candidates; however, challenges remain in terms of device performance and durability. We have developed organic field-effect transistor (OFET) memories using precisely designed polymer materials as the memory layer (floating gate), which plays a key role in charge storage. By taking advantage of the structural versatility of organic materials, we aim to tune device performance through molecular and nanostructural design and to develop new materials suitable for wearable electronics.