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Manipulating Pico- to Nanoliter Droplets on Surfaces without Sticking

ACS Nano 19 [45] 39398-39406. 2025.

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Liquid-repellent technologies for pico- to nanoliter droplets enable downsized fluid manipulation

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Liquid-repellent surfaces prevent droplets from sticking and have therefore been used as platforms for droplet manipulation. However, conventional technologies could only repel microliter-scale droplets, and preventing the adhesion of smaller droplets has remained a challenge. Here, we discovered that picoliter- to nanoliter-sized droplets do not adhere to the substrate when their surfaces are coated with super-omniphobic fumed titania nanoparticles. Using this technique, we developed diverse methods for manipulating a wide range of ultraminiature droplets. This research contributes to the further downscaling of fluidic devices.

Fulltext and dataset(s) on Materials Data Repository (MDR)


Created at: 2025-11-20 03:11:25 +0900 Updated at: 2026-09-30 06:07:12 +0900

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