Toward the Establishment of a Harmonized Physicochemical Profiling Platform for Therapeutic Oligonucleotides: A Case Study for Aptamers Where the Higher-Order Structure Influences Physical Properties

Shoko Takeuchi; Tomohiko Yamazaki; Katsutoshi Yamaguchi; Fusae Komura; Takahiro Tabata; Hirotaka Nishi; Satomi Azumai; Kanako Miura; Mai Hirokawa; Keisuke Ikemoto; Kohsaku Kawakami; Shoko Takeuchi; Tomohiko Yamazaki; Katsutoshi Yamaguchi; Fusae Komura; Takahiro Tabata; Hirotaka Nishi; Satomi Azumai; Kanako Miura; Mai Hirokawa; Keisuke Ikemoto; Kohsaku Kawakami

doi:10.1021/acs.molpharmaceut.4c00177

Toward the Establishment of a Harmonized Physicochemical Profiling Platform for Therapeutic Oligonucleotides: A Case Study for Aptamers Where the Higher-Order Structure Influences Physical Properties

Shoko Takeuchi, Tomohiko Yamazaki, Katsutoshi Yamaguchi, Fusae Komura, Takahiro Tabata, Hirotaka Nishi, Satomi Azumai, Kanako Miura, Mai Hirokawa, Keisuke Ikemoto, Kohsaku Kawakami.

Molecular Pharmaceutics 21 [7] 3471-3484. 2024.

https://doi.org/10.1021/acs.molpharmaceut.4c00177

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Fulltext and dataset(s) on Materials Data Repository (MDR)

Created at: 2024-10-05 03:14:28 +0900Updated at: 2024-12-08 09:43:48 +0900